Sökning: "BCG"
Visar resultat 11 - 15 av 58 avhandlingar innehållade ordet BCG.
11. T cell mediated immunity in malaria and mycobacterial infection : a protective role for gd+ T cells
Sammanfattning : T cell mediated immunity is essential against intracellular infections. Studies of cell mediated immunity are important for the optimal design and development of effective vaccines. Identifying correlates of protective immunity will also enable measurement of vaccine efficiency. LÄS MER
12. Dendritic cell migration to draining lymph node and T-cell priming to Bacille Calmette-Guérin
Sammanfattning : Dendritic cells (DCs) are unique antigen presenting cells that bridge innate and adaptive immunity. DCs sense invading microbes, sample antigen and migrate to the draining lymph node (DLN) where they prime T cells to the microbe. LÄS MER
13. Novel immunization strategies and interethnic differences in response to malaria infection
Sammanfattning : A better understanding of the role of antigen-presenting cells (APCs) in host resistance to malaria is essential to unravel the complex interactions between the host and the parasite. This would improve the design of malaria vaccines. LÄS MER
14. Defining the role of migratory dendritic cells in priming T cells to mycobacteria
Sammanfattning : Dendritic cells (DCs) are professional antigen-presenting cells that bridge innate and adaptive immunity by priming T cells. DCs residing at body surfaces such as skin sense invading microbes and respond by internalizing the microbe at the site of infection and subsequently migrating to the draining lymph node (dLN) where they present microbial antigen and other requisite signals to T cells that arm the T cells to fight-off the infection. LÄS MER
15. Diagnostic biomarkers and improved vaccination against mycobacterial infection
Sammanfattning : Tuberculosis (TB) remains one of the world’s most serious infectious diseases. It is estimated that a third of the world’s population is latently infected and 8 million new cases are recorded each year. LÄS MER