Sökning: "BCG vaccine"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden BCG vaccine.

  1. 1. Heat shock proteins as vaccine adjuvants

    Författare :Khaleda Rahman Qazi; Carmen Fernández; Qijun Chen; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heat shock protein; vaccine; adjuvant; BCG; Immunology; Immunologi;

    Sammanfattning : New efficient vaccines against infectious diseases are in demand. Some important factors impeding the vaccine development are the poor immunogenicity and the MHC restriction of the immune responses to a number of antigens. LÄS MER

  3. 2. Studies on new tuberculosis vaccine candidates in animal models

    Författare :Melles Haile; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Tuberculosis (TB) is a major health problem in many countries, especially in low income countries. Globally, TB causes more than 2 million human deaths annually and 1/5 of all adult deaths in developing countries. WHO estimates that one third of the world's population i.e. LÄS MER

  4. 3. A role for NK cells in innate immunity against human leishmaniasis

    Författare :Susanne Nylén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Leishmania; NK cells; innate immune activation; IFNgamma; vaccine candidates;

    Sammanfattning : Leishmaniasis is a group name for a spectrum of diseases caused by intracellular protozoa belonging to the family Leishmania. The parasites has been widely used as a tool to study the Th1 / Th2 paradigm of resistance and susceptibility in mice. A role of NK cells in leishmaniasis has been implicated, but not fully explored. LÄS MER

  5. 4. T cell mediated immunity in malaria and mycobacterial infection : a protective role for gd+ T cells

    Författare :Shewangizaw Worku; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Malaria; Plasmodium falciparum; Plasmodium. vivax; Mycobacteria; Mycobacterium tuberculosis; BCG; T lymphocytes; T cell receptor; [gamma][delta] T cells; [alpha][beta] T cells;

    Sammanfattning : T cell mediated immunity is essential against intracellular infections. Studies of cell mediated immunity are important for the optimal design and development of effective vaccines. Identifying correlates of protective immunity will also enable measurement of vaccine efficiency. LÄS MER

  7. 5. Novel immunization strategies and interethnic differences in response to malaria infection

    Författare :Charles Arama; Marita Troye-Blomberg; Kai Matuschewski; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Malaria; Immunization; Ethnic groups; vaccines; immunologi; Immunology;

    Sammanfattning : A better understanding of the role of antigen-presenting cells (APCs) in host resistance to malaria is essential to unravel the complex interactions between the host and the parasite. This would improve the design of malaria vaccines. LÄS MER