Sökning: "B-regulatory cells"

Hittade 4 avhandlingar innehållade orden B-regulatory cells.

  1. 1. Pinpointing biomarkers of importance for children with combined type 1 diabetes and celiac disease

    Författare :Andrea Tompa; Maria Faresjö; Karin Åkesson; Mikael Karlsson; Jönköping University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; celiac disease; children; biomarkers; immune markers; flow cytometry; cryopreservation; T cells; T-regulatory cells; B cells; B-regulatory cells; cytokines; chemokines; acute phase proteins; adipocytokines; matrix metalloproteinases;

    Sammanfattning : Type 1 diabetes (T1D) and celiac disease are both characterized by an autoimmune feature. The diseases also share the same risk genes, and thereby patients have an increased risk of developing the other disease subsequently. LÄS MER

  3. 2. Transforming Growth Factor-b, Regulatory functions on normal lymphocytes and tumor outgrowth Regulatory functions on normal lymphocytes and tumor outgrowth

    Författare :Åsa Schiött; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TGF-b; monocyte; rat; costimulation; Th2; ERK; tumor; TIL; Immunology; serology; Immunologi; transplantation; T-lymphocyte; serologi;

    Sammanfattning : Transforming growth factor-beta (TGF-b) is a well-characterised growth regulatory factor, which acts on most cell types. This thesis has focused on the regulatory roles of TGF-b on normal lymphocytes. One interesting finding is that TGF-b acts both costimulatory and inhibitory on T-lymphocytes. LÄS MER

  4. 3. Presence of immunological markers preceding the onset of rheumatoid arthritis

    Författare :Mikael Brink; Solbritt Rantapää Dahlqvist; Anca Irinel Catrina; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoantibodies; rheumatoid arthritis; anti citrullinated protein antibodies; pre-symptomatic individual; immunologi; Immunology; reumatologi; rheumatology;

    Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory disease with an unknown aetiology characterized by joint destruction. Both genetic and environmental factors contribute to the disease development with HLA-DRB1* alleles and smoking identified as most important. LÄS MER

  5. 4. Diabetes Mellitus at the Time for Diagnosis : Studies on Prognostic Factors

    Författare :Mats Martinell; Jan Stålhammar; Johan Hallqvist; Mozhgan Dorkhan; Claes-Göran Östenson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; New-onset Diabetes Mellitus; socioeconomic position; epidemiology; diabetes complications; diabetic retinopathy; cellular immunology; diabetes classification; type 2 diabetes; latent autoimmune diabetes in adults LADA ; type 1 diabetes; Allmänmedicin; Family Medicine; Endokrinologi och Diabetologi; Endocrinology and Diabetology;

    Sammanfattning : The aim for this thesis was to identify prognostic factors for chronic diabetes complications that exist at the time of diabetes diagnosis.Low level of education (... LÄS MER