Sökning: "B lymphocytes"

Visar resultat 11 - 15 av 284 avhandlingar innehållade orden B lymphocytes.

  1. 11. The B lymphocyte in Staphylococcus aureus arthritis

    Författare :Inger Gjertsson; Göteborgs universitet; []
    Nyckelord :Staphylococcus aureus; mice; arthritis; sepsis; B cells; Fcg receptors; CD22; ; IL-4; IL-10; IFN-g.;

    Sammanfattning : Joint infection caused by Staphylococcus aureus leads to heavy synovitis and rapid destruction of bone and cartilage. Permanent loss of joint function is seen in 20-50% of the patients, despite early eradication of the bacteria with antibiotics. LÄS MER

  3. 12. Studies on Molecular Genetics of B cell Development

    Författare :Panagiotis Tsapogas; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunoglobulin; gene expression; B cell; EBF; class switching; TGF-beta; Immunology; transplantation; serologi; Immunologi; serology;

    Sammanfattning : The development of immature progenitor cells into highly differentiated effector cells is a process central in modern medicine with applications in the fields of cell therapy as well as oncology. This thesis is focused on the molecular mechanisms that control the development of B lymphocytes. LÄS MER

  4. 13. Molecular genetics of B- and T-lymphocyte development

    Författare :Ingela Wikström; Dan Holmberg; Inga-Lill Mårtensson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lymphocyte development; Dmu protein; transcription factor; bHLH; E2-2; T cell; B cell; marginal zone; Medical genetics; Medicinsk genetik;

    Sammanfattning : Lymphocytes are essential for the generation of specific immunity. Development of B cells in the bone marrow and T cells in the thymus have several analogous features, and are tightly regulated processes. Even though there is an increasing amount of information concerning lymphopoiesis, a lot of questions remain. LÄS MER

  5. 14. Links between activation and cytoskeletal regulation of B lymphocytes

    Författare :Gediminas Greicius; Edvard Smith; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Zoological Developmental Biology; zoologisk utvecklingsbiologi;

    Sammanfattning : Interplay between adhesion molecules and the cytoskeleton is involved in many aspects of B lymphocyte behaviour during an immune response. Events such as cell polarisation and locomotion, collaboration with T lymphocytes and segregation in secondary lymphoid tissues all include mechanisms that recognise microenvironment and accordingly adjust morphological features of the cell. LÄS MER

  7. 15. Biosynthesis and biological role of leukotrienes in B lymphocytes

    Författare :Yilmaz Mahshid; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Leukotrienes (LT) are potent lipid mediators, synthesized from arachidonic acid (AA) upon cell activation. The essential enzyme for leukotriene biosynthesis is 5-lipoxygenase (5-LO), converting AA, through a two step process to LTA4. The activity of 5-LO is dependent on 5-lipoxygenase activating protein (FLAP). LÄS MER