Sökning: "B Lindqvist"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden B Lindqvist.

  1. 1. The genetics of systemic lupus erythematosus : Mapping of susceptibility loci for human SLE

    Författare :Anna-Karin B. Lindqvist; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Systemic lupus erythematosus; complex diseases; genetic susceptibility; linkage analysis; genome scan; candidate gene; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

    Sammanfattning : Systemic lupus erythematosus (SLE) is a systemic autoimmune disease affecting organs such as skin, jointsand kidneys. Characteristic for the disease is increased production of autoantibodies, in particular against dsDNA. Previous studies of SLE in mouse models and in humans indicate polygenic inheritance and genetic heterogeneity. LÄS MER

  3. 2. T Regulatory Cells – Friends or Foes?

    Författare :Camilla Lindqvist; Angelica Loskog; Thomas Tötterman; Vivianne Malmström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Treg; T regulatory cell; FoxP3; CD25; CLL; B-cell lymphoma; Clinical immunology; Klinisk immunologi; Klinisk immunologi; Clinical Immunology;

    Sammanfattning : T regulatory cells (Tregs) have been extensively studied in patients with cancer or autoimmunity. These cells hamper the immune system’s ability to clear tumor cells in cancer patients. In autoimmune diseases, on the other hand, they are not able to restrain autoreactive immune responses. LÄS MER

  4. 3. Regulation of CDK dephosphorylation in mitotic entry

    Författare :Arne Lindqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cell cycle progression is orchestrated by the activity of a Cyclin dependent kinase (Cdk) in complex with a Cyclin. The key regulator of early mitotic events is the Cyclin B1/Cdk1 complex. In G2, Cyclin B1/Cdk1 is kept inactive by phosphorylation in the active site of Cdk1. LÄS MER

  5. 4. Structural and evolutionary studies of a lipocalin: the alpha1-microglobulin protein and its gene

    Författare :Annika Lindqvist; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; embryology human ; ontogeny; teratology; AMBP; Development biology; protein HC; bikunin; Utvecklingsbiologi; teratologi; embryologi människa ; Genetics; cytogenetics; Genetik; cytogenetik;

    Sammanfattning : a1-microglobulin is a small glycoprotein present in plasma and in tissues surrounding the gastrointestinal and respiratory tracts. a1-microglobulin is a member of the lipocalin protein family and exhibits several of the typical traits of a lipocalin; it binds an unknown ligand which causes the brown color of the protein, it forms complexes with various different proteins and there have been indications of the presence of a receptor for a1-microglobulin on T-lymphocytes. LÄS MER

  7. 5. Promoting adolescents' physical activity @ school

    Författare :Anna-Karin Lindqvist; Ann Öhman; Luleå tekniska universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiotherapy; Fysioterapi;

    Sammanfattning : The overall aim of this thesis was to explore the development of a health-promoting intervention that uses empowerment and information and communication technology, to examine the impact of the intervention and to describe adolescents' and parents' experiences of the intervention. This thesis includes four studies, three of which used a qualitative approach (I, III and IV) and one of which used a mixed method approach (II). LÄS MER