Sökning: "Axonal Guidance"

Visar resultat 1 - 5 av 16 avhandlingar innehållade orden Axonal Guidance.

  1. 1. Controlled axonal outgrowth and cell reactions to nanostructures

    Författare :Fredrik Johansson; Funktionell zoologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Contact guidance; neuron; axon; fibroblast; macrophage; polymethylmethacrylate; porous silicon; nanowire; magnetic; immunoresponse; nanoimprint lithography; haptotaxis;

    Sammanfattning : The interface between living cells and artificial surfaces are highly relevant for biomedical applications such as implants and organized cell growth for tissue reconstruction as well as for basic science purposes. In the present thesis, we have studied axonal guidance on various nano-patterned surfaces such as polymethyl-meth-acrylate, porous silicon and on magnetically aligned Ni nanowires. LÄS MER

  3. 2. Studies on Peripheral Nerve Regeneration: Microdispensing, Neurite Guidance and Galectins

    Författare :Per Gustavsson; Funktionell zoologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; vävnadskultur; histokemi; cytokemi; Histologi; tissue culture; histochemistry; cytochemistry; Histology; Schwann cells; sciatic nerve; dorsal root ganglia; DRG; neurite guidance; galectins; inkjet; microdispensing; peripheral nervous system; nerve regeneration; Animal physiology; Djurfysiologi; Biotechnology; Bioteknik;

    Sammanfattning : The present thesis describes development of a microdispenser-based technique to create of protein patterns for neurite guidance. The same technique was also developed to allow direct positioning of dissociated cells, including neurons, on cell culture substrates. Finally the role of galectin-3 and 8 during nerve regeneration was investigated. LÄS MER

  4. 3. Machine Learning Techniques with Specific Application to the Early Olfactory System

    Författare :Benjamin Auffarth; Anders Lansner; Tony Lindeberg; Tim Pearce; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; feature selection; image features; pattern classification; relevance; redundancy; distributional similarity; divergence measure; genetic algorithms; clustering algorithms; annealing; olfactory coding; olfactory bulb; odorants; glomeruli; property-activity relationship; olfaction; plasticity; axonal guidance; odor category; perception; spatial coding; population coding; memory organization; odor quality; SRA - ICT; SRA - Informations- och kommunikationsteknik;

    Sammanfattning : This thesis deals with machine learning techniques for the extraction of structure and the analysis of the vertebrate olfactory pathway based on related methods. Some of its main contributions are summarized below. LÄS MER

  5. 4. Nanowires for Cell Research

    Författare :Waldemar Hällström; Fasta tillståndets fysik; []
    Nyckelord :Nanotoxicology; Nanowires; Nanotubes; Nerve Cells; Cell Probing; Force Measurements; Nanotechnology; Axonal Guidance; Fysicumarkivet A:2010:Hällström;

    Sammanfattning : This study explores the interaction between living biological cells and semiconductor nanowires. Biological cells are highly complex and dynamic entities, every one of them with individual characteristics and a high degree of internal and external communication. LÄS MER

  7. 5. Molecular mechanisms of nerve-tumor interactions : the intersection of cancer and neurodevelopment

    Författare :Luz Maria Gonzalez-Castrillon; Sara I Wilson; Daniel Öhlund; Nisha D’Silva; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Perineural invasion; cancer; PDAC; axonogenesis; neurodevelopment; spinal cord; axon guidance; bioinformatics.; biomedical laboratory science; biomedicinsk laboratorievetenskap;

    Sammanfattning : A wide range of cancers throughout the body are characterized by high nerve density and invasion of cancer cells within the nerves, a process called perineural invasion (PNI). Work in the field has shown that blocking nerves in organs with tumors leads to improved disease outcomes suggesting that finding ways to block tumor nerves could lead to new treatment approaches. LÄS MER