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  1. 1. Immunological mechanisms in systemic autoimmunity : autoantibodies and chemokines in systemic lupus erythematosus and during treatment with TNF inhibitors in rheumatoid arthritis

    Författare :Catharina Eriksson; Karl-Gösta Sundqvist; Solbritt Rantapää-Dahlqvist; Mari Norgren; Thomas Skogh; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoimmunity; chemokines; T-cells; autoantibodies; CD91; Clinical immunology; Klinisk immunologi; Rheumatology; Reumatologi; Clinical Immunology; klinisk immunologi; reumatologi; rheumatology;

    Sammanfattning : Background. Rheumatoid Arthritis (RA) is an autoimmune inflammatory disease that, without powerful treatment, may lead to irreversible joint damage. During the past decade, anti-cytokine therapy has become available, e.g. LÄS MER

  3. 2. Mercury-induced autoimmunity : Genetics and immunoregulation

    Författare :Monika Hansson; Manuchehr Abedi-Valugerdi; Marita Troye-Blomberg; Lucette Pelletier; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mercury; autoimmunity; collagen-induced arthritis; Th1 Th2; silver; tight-skin 1 mice; Immunology; Immunologi;

    Sammanfattning : The existence of immune self-tolerance allows the immune system to mount responses against infectious agents, but not against self-molecular constitutes. Although self-tolerance is a robust phenomenon, in some individuals as well as in experimental models, the self-tolerance breaks down and as a result, a self-destructive autoimmune disease emerges. LÄS MER

  4. 3. Effect of thimerosal on the murine immune system : especially induction of systemic autoimmunity

    Författare :Said Havarinasab; Per Hultman; Klas Nordlind; Linköpings universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; thimerosal; ethylmercury; autoimmunity; mice; immunosuppression; Th1; Th2; Pathology; Patologi;

    Sammanfattning : The organic mercury compound ethylmercurithiosalicylate (thimerosal), an antiseptic and a preservative, has recently raised public health concern due to its presence in vaccines globally. Thimerosal dissociates in the body to thiosalicylate and ethyl mercury (EtHg), which is partly converted to inorganic mercuric mercury (Hg2+). LÄS MER

  5. 4. Apoptosis in cancer and autoimmunity

    Författare :Mounira Djerbi; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Apoptosis; Autoimmunity; Neoplasms;

    Sammanfattning : .... LÄS MER

  7. 5. Neutrophils and autoantibodies in autoimmune rheumatic disease

    Författare :Sabine Arve-Butler; Lund Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neutrophils; Autoantibodies; Autoimmunity; Rheumatic diseases; Juvenile idiopathic arthritis; Systemic Lupus Erythematosus;

    Sammanfattning : .... LÄS MER