Sökning: "Aurora kinases"

Hittade 2 avhandlingar innehållade orden Aurora kinases.

  1. 1. Histone modification regulated bysuppressor of Zeste 12 and Ipl1 Aurora-like kinase in Drosophila

    Detta är en avhandling från Umeå : Umeå universitet, Institutionen för molekylärbiologi

    Författare :Anna Larsson; Umeå universitet.; [2010]
    Nyckelord :molekylär bioteknik inst f molekylärbiologi ; Molecular Biotechnology;

    Sammanfattning : Polycomb group (PcG) proteins are a group of genome wide silencers that are crucial for many processes during the development. In Drosophila PcG proteins are organised into four different complexes: PRC1, PRC2, PhoRC and PR-DUB. PRC2 consists of four core proteins: Su(z)12, E(z), Esc and Nurf. LÄS MER

  2. 2. Myc-induced Lymphomagenesis In vivo assessment of downstream pathways

    Detta är en avhandling från Umeå : Umeå universitet, Institutionen för molekylärbiologi

    Författare :Sara Rimpi; Umeå universitet.; [2010]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Myc; lymphomagenesis; Aurora kinases; polyamine; glycolysis; targeting; mouse models of cancer; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Myc oncogenes encode transcription factors that bind to E-box sequences in DNA, driving the expression of a large number of target genes and are deregulated in approximately 70% of human cancers. Deregulated Myc expression cause enhanced proliferation (which is counteracted by apoptosis), angiogenesis and cancer. LÄS MER