Sökning: "Atox1"
Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet Atox1.
1. Copper-transporting proteins and their interactions with platinum-based anticancer substances
Sammanfattning : Cisplatin (CisPt) is an important drug that is used against various cancers, including testicular, ovarian, lung, head, and neck cancer. However, its effects are limited by cellular resistance. LÄS MER
2. COPPER BINDING PROTEINS IN BREAST CANCER : CELLULAR AND MOLECULAR MECHANISMS
Sammanfattning : Cancer is one of the leading causes of human death. However, the mechanisms governing cancer are still not fully understood. Elevated levels of copper (Cu) have been observed in both cancerous tissues and the serum of cancer patients. LÄS MER
3. Roles of intermolecular interactions in amyloid fibril formation mechanisms
Sammanfattning : Amyloid fibrils, a major pathological feature of several neurodegenerative disorders, are highly stable, insoluble aggregates of misfolded proteins. The formation of such aggregates involves a complex equilibrium between protein monomers, different on- and off-pathway transient oligomeric species, and amyloid fibrils. LÄS MER
4. Engineering Yeast for Functional Analysis of Human Cu Transport Proteins
Sammanfattning : ABSTRACT Copper (Cu) is an important trace element that plays a vital role in several biological processes. Many proteins that are involved in various biochemical pathways require Cu as a cofactor. LÄS MER
5. Human copper ion transfer : from metal chaperone to target transporter domain
Sammanfattning : Many processes in living systems occur through transient interactions among proteins. Those interactions are often weak and are driven by small changes in free energy. LÄS MER