Sökning: "Assay optimisation"

Visar resultat 11 - 14 av 14 avhandlingar innehållade orden Assay optimisation.

  1. 11. Design and Synthesis of Galectin Inhibitors

    Författare :Pernilla Sörme; Barbro Kahl Knutson; U Wellmar; B-G Magnusson; Hakon Leffler; Ulf Nilsson; Yuan C. Lee; Reiko T. Lee; Centrum för analys och syntes; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parallel Synthesis; Inhibitors; Biomedicinska vetenskaper allmänt ; General biomedical sciences; Carbohydrates; Galectins;

    Sammanfattning : Galectins, a lectin family, have shown binding affinities towards b-galactosides. Galectins have been proposed to be involved in a wide range of functions like for example, cell growth, adhesion, migration, chemo taxis and apoptosis. They have also been associated with various cancer types. LÄS MER

  3. 12. Bioprocess development for biochemical conversion of lignocellulose

    Författare :Ruifei Wang; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Lignocellulose; strain engineering; stress tolerance; kinetic modelling; high gravity; scale-up; biofuels; SSCF; process development; Saccharomyces cerevisiae;

    Sammanfattning : Due to its low environmental impact and high maturity of the fuel ethanol market, lignocellulosic ethanol is a promising option for reducing the carbon footprint in the transport sector. The characteristics of lignocellulosic feedstocks, such as varied sugar composition, low sugar density, low solubility, recalcitrance to enzymatic degradation, and inhibitors formed during thermochemical pretreatment, have so far limited the production process, and costs for conversion of lignocellulosic materials to ethanol are still high. LÄS MER

  4. 13. Process Analytical Tools for the Monitoring and Characterization of Bacterial Toxins

    Författare :Martin Hedström; Bioteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Bioteknik; Biotechnology; protein degradation; mass spectrometry; Bacterial toxins; Biosensor;

    Sammanfattning : In the era of proteomics, glycomics and ultimately metabolomics, with constantly increasing knowledge regarding the human biosystem, the number of specialized therapeutic agents which will be developed against different diseases is predicted to be on the upswing. An increasing portion of these new drugs will, according to recent predictions (Labrou, 2003), be of proteinaceous origin produced according to biotechnological standards. LÄS MER

  5. 14. The Propagation of Neurodegenerative Diseases by Inflammation and Exosomes

    Författare :Valerie Sackmann; Martin Hallbeck; Camilla Nilsberth; Anna Ansell-Schultz; Maitrayee Sardar Sinha; Tomas Deierborg; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the two most common neurodegenerative diseases with rates increasing along with the ageing global population. Despite best efforts, we still do not understand the etiopathogenesis of these diseases and there are no effective disease-modifying treatments. LÄS MER