Sökning: "Aseptic loosening"

Visar resultat 1 - 5 av 34 avhandlingar innehållade orden Aseptic loosening.

  1. 1. Aseptic Loosening of Orthopedic Implants : Osteoclastogenesis Regulation and Potential Therapeutics

    Författare :Mehdi Amirhosseini; Anna Fahlgren; Göran Andersson; Teun J. de Vries; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Aseptic loosening is the main cause of failure of orthopedic prostheses. With no pharmaceuticals to prevent or mitigate periprosthetic bone degradation, a surgery to replace the loose implant with a new one is the only choice to restore patients’ function. LÄS MER

  3. 2. On the aetiology of aseptic loosening in joint arthroplasties, and routes to improved cemented fixation

    Författare :Mikael Sundfeldt; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; knee prosthesis; aseptic loosening; polyethylene particles; endotoxin; bone cement; sodium fluoride;

    Sammanfattning : Background: Aseptic loosening is the most common single cause for revisions in major joint arthroplasties worldwide. Different theories for aseptic loosening have been discussed during the last two decades. There is a need for improving fixation in both cemented and uncemented implants. LÄS MER

  4. 3. Biological aspects of synovial fluid mediated aseptic prosthesis loosening

    Författare :Martin Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Aseptic loosening; synovial fluid; osteoblasts; bone resorption; IGF;

    Sammanfattning : Aseptic prosthesis loosening is the most common reason for late failure of total hip arthroplasties. Resorption of the peri-prosthetic bone, resulting in a loose prosthesis is characteristic for aseptic loosening. LÄS MER

  5. 4. Kinematics and fixation of total knee arthroplasties : a clinical, radiographic, scintimetric, and roentgen stereophotogrammetric evaluation

    Författare :Kjell G. Nilsson; Johan Kärrholm; Leif Ryd; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Total knee arthroplasty; tibial component; kinematics; micromotion; loosening; scintimetry; roentgen stereophotogrammetric analysis;

    Sammanfattning : Aseptic loosening of the tibial component is an important cause of failure after total knee arthroplasty. Bone destruction often claimed to be caused by the cement makes the revision difficult. In order to treat younger patients, uncemented fixation has been introduced, but the etiology to loosening is multifactorial and only partly known. LÄS MER

  7. 5. On loosening and revision in total hip arthroplasty

    Författare :Thomas Eisler; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Aseptic loosening; osteolysis; septic loosening; revision; revision total hip arthroplasty; total hip arthroplasty;

    Sammanfattning : Periprosthetic bone resorbtion (osteolysis) and aseptic loosening constitute the major long-term complication in total hip arthroplasty. It has been suggested that osteolysis is the result of the action of osteoclasts generated by prosthetic wear-debris-triggered macrophages. LÄS MER