Sökning: "Aquaporin-4"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet Aquaporin-4.

  1. 1. Methods to study glymphatic system in the rodent brain during physiological and pathological processes

    Författare :Roberta Battistella; Glia-Immune Interactions; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glymphatic system; Aquaporin-4; Lectins; Parkinson´s disease; α-synuclein; Hypothermia;

    Sammanfattning : Over the past decade, our understanding of brain-waste clearance underwent a revolution after the discovery of the so-called glymphatic system. The glia-lymphatic (abbreviated, glymphatic) system was first described in 2012 as a paravascular macrosystem involved in the distribution of nutrients and clearance of metabolic waste from the brain parenchyma. LÄS MER

  2. 2. Studies on aquaporin 4 : a molecular determinant of brain water homeostasis

    Författare :Eli Gunnarson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : A well controlled brain water homeostasis is of utmost importance for an appropriate control of neuronal activity. Astrocytes express the water channel aqauporin 4 (AQP4) and play a key role for the maintenance of brain water homeostasis. Brain edema is a result of perturbed water homeostasis and involves astrocyte swelling. LÄS MER

  3. 3. AQUAPORINS: Production Optimization and Characterization

    Författare :Fredrik Öberg; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Aquaporins are water facilitating proteins embedded in the cellular membranes. Such channels have been identified in almost every living organism – including humans. They are vital molecules and their malfunction can lead to several severe disorders. LÄS MER

  4. 4. Dementia Proteomics

    Författare :Julia Remnestål; Peter Nilsson; Anna Månberg; Pieter Jelle Visser; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dementia; Proteomics; Alzheimer s disease; Frontotemporal dementia; Antibody array; Suspension bead array; Cerebrospinal fluid; Protein profiling; Biomarker discovery; Bioteknologi; Biotechnology;

    Sammanfattning : The term dementia encompass a number of conditions arising as a consequence of tissue degeneration in the brain. This degeneration is caused by molecular events occurring on a cellular level including inflammation, defective waste disposal and accumulation of insoluble proteins and peptides. LÄS MER

  5. 5. Housing Aquaporins in Nanostructured Glass

    Författare :Simon Isaksson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Membrane protein; Water; Interface; Aquaporin; Silica; Formation; Silicification;

    Sammanfattning : Proteins are a group of biomolecules that perform versatile tasks, which in many cases are essential for life. The magnitude of their importance is perhaps expressed by the word protein itself, coined by the Swedish chemist Jöns Jacob Berzelius in the summer of 1838. LÄS MER