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Visar resultat 1 - 5 av 333 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Microfluidic Compartmentalization for Smart Materials, Medical Diagnostics and Cell Therapy

    Författare :Emre Iseri; Wouter van der Wijngaart; Nicole Pamme; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Microfluidics; microfabrication; compartmentalization; partitioning; droplet microfluidics; self-assembly; 3D microarrays; soft composites; beads; particles; core-shell particle; point-of-care; diagnostics; dipstick; digital bioassays; lab-on-a-chip; urinary tract infection; bacteria detection; E. coli; cell encapsulation; hydrogel; cell therapy; spider silk; magnetic metamaterials.; Mikrofluidik; mikrotillverkning; kompartmentalisering; partitionering; droppmikrofluidik; självmontering; 3D-mikromatriser; mjuka kompositer; pärlor; partiklar; kärna-skalpartikel; vårdpunkt; diagnostik; mätsticka; digitala bioanalyser; laboration-a-chip; urinvägsinfektion; bakteriedetektering; E. coli; cellinkapsling; hydrogel; cellterapi; spindelsilke; magnetiska metamaterial.;

    Sammanfattning : The organisation of fluids in small compartments is ubiquitous in nature, such as in the cellular composition of all life. This work explores several engineering avenues where microscale fluid compartmentalization can bring novel material properties or novel functionality in life sciences or medicine. LÄS MER

  2. 2. Mesoporous Implants for Localized Controlled Drug Delivery

    Författare :Johan Karlsson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; release kinetics; mesoporous titania; biomineralization; drug delivery; Biomedical implants; osseointegration; osteoporosis drugs; nanotopography; stem cells homing;

    Sammanfattning : The use of bone-anchored implants is today a routine treatment for patients with normal regenerative capacity. However, there is an ongoing development within implant research to improve the osseointegration of implants. LÄS MER

  3. 3. A Sound Approach Toward a Mobility Aid for Blind and Low-Vision Individuals

    Författare :Johan Isaksson-Daun; Avdelningen för Biomedicinsk teknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Audomni; Blindness; Electronic travel aids; Desire of Use; DoU-MoB; DoUQ-MoB; Low vision; Mobility aids; Parrot-VR; Paitient-reported outcome measures; Sonification; Sensory substitution; Sensory supplementation; Virtual environments; Virtual reality; Visual impairment; Audomni; Blindhet; Electronic travel aids; Desire of Use; DoU-MoB; DoUQ-MoB; Kraftig synnedsättning; Förflyttningshjälpmedel; Orienteringshjälpmedel; Parrot-VR; Patient-reported outcome measures; Sonification; Sensory substitution; Sensory supplementation; Virtual environments; Virtual reality; Synnedsättning;

    Sammanfattning : Reduced independent mobility of blind and low-vision individuals (BLVIs) cause considerable societal cost, burden on relatives, and reduced quality of life for the individuals, including increased anxiety, depression symptoms, need of assistance, risk of falls, and mortality. Despite the numerous electronic travel aids proposed since at least the 1940’s, along with ever-advancing technology, the mobility issues persist. LÄS MER

  4. 4. Development of Techniques for Characterization, Detection and Protein Profiling of Extracellular Vesicles

    Författare :Sara Cavallaro; Jan Linnros; Apurba Dev; Hakho Lee; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular vesicles; streaming current; fluorescence microscopy; atomic force microscopy; scanning electron microscopy; protein profiling; size profiling; Biological and Biomedical Physics; Biologisk och biomedicinsk fysik;

    Sammanfattning : Nanosized extracellular vesicles (EVs, ∼30-2000 nm) have emerged as important mediators of intercellular communication, offering opportunities for both diagnostics and therapeutics. In particular, small EVs generated from the endolysosomal pathway (∼30-150 nm), referred to as exosomes, have attracted interest as a suitable biomarker for cancer diagnostics and treatment monitoring based on minimally invasive liquid biopsies. LÄS MER

  5. 5. Non-invasive imaging for improved cardiovascular diagnostics : Shear wave elastography, relative pressure estimation, and tomographic reconstruction

    Författare :David Marlevi; Matilda Larsson; Reidar Winter; Massimiliano Colarieti-Tosti; Kathryn Nightingale; KTH; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Medical imaging; Cardiovascular disease; Atherosclerosis; Hemodynamics; Ultrasound; Shear Wave Elastography SWE ; Magnetic Resonance Imaging MRI ; 4D flow MRI; Relative Pressure; Virtual Work-Energy; micro-Computed Tomography micro-CT ; Tomographic reconstruction; Pre-clinical imaging; Medicinsk avbildning; Hjärt-kärlsjukdomar; Ateroskleros; Hemodynamik; Ultraljud; Skjuvvågselastografi SWE ; Magnetresonanstomografi MRI ; 4D flödes-MRI; Tryckfall; Virtuellt flöde; mikro-Datortomografi mikro-CT ; Tomografisk rekonstruktion; Preklinisk avbildning; Medicinsk teknologi; Medical Technology;

    Sammanfattning : Throughout the last century, medical imaging has come to revolutionise the way we diagnose disease, and is today an indispensable part of virtually any clinical practice. In cardiovascular care imaging is extensively utilised, and the development of novel techniques promises refined diagnostic abilities: ultrasound elastography allows for constitutive tissue assessment, 4D flow magnetic resonance imaging (MRI) enables full-field flow mapping, and micro-Computed Tomography (CT) permits high-resolution imaging at pre-clinical level. LÄS MER