Sökning: "Apoptotic bodies"
Visar resultat 1 - 5 av 22 avhandlingar innehållade orden Apoptotic bodies.
1. Horizontal gene transfer by uptake of apoptotic bodies
Sammanfattning : In adults as well as during embryogenesis, apoptosis plays a key role in the elimination of cells in multicellular organisms. Apoptosis is important for the maintenance of tissue homeostasis. It is also of importance in tumor development, where tumor cells die by apoptosis due to low levels of oxygen and nutrients. LÄS MER
2. Extracellular Vesicles and RNA interference in tumors
Sammanfattning : Extracellular vesicles (EVs) including apoptotic bodies (ABs), microvesicles (MVs), exosomes (EXOs) and cell derived artificial nanovesicles (NVs) are important mediators of cell-to-cell communication, in part by transferring bioactive molecules such as DNA, mRNA, miRNA, siRNA, proteins, and lipids. These EVs are released by many cell types, including melanoma cells, and are found in many body fluids. LÄS MER
3. Immunological properties of dendritic cells in HIV-1 infection
Sammanfattning : Dendritic cells (DCs) capture antigens for intracellular processing to form MHC-peptide complexes involved in the generation of antigen specific T cell responses. After encountering microbes, DCs migrate from the periphery to the regional lymph nodes. LÄS MER
4. Cell death and clearance - studies of human neutrophils from blood and tissue
Sammanfattning : Neutrophils are phagocytic cells that typically migrate from circulation to tissues in order to combat microbial invasion. The journey from blood to tissue involves mobilization of intracellular organelles which results in modifications of surface markers (e.g. LÄS MER
5. On the mechanisms and consequences of cell to cell DNA transfer
Sammanfattning : Development of cancer is a multistep process where an accumulation of genetic alterations drives normal cells to malignancy. In most cancer cells genetic changes can be observed both at the level of point mutations and as gains and losses of chromosomes. LÄS MER