Sökning: "ApoB"
Visar resultat 11 - 15 av 57 avhandlingar innehållade ordet ApoB.
11. Mechanisms behind the lipid-lowering effects of ACTH - Studies in different experimental models
Sammanfattning : Abstract Adrenocorticotrophic hormone (ACTH) has strong and direct lipid-lowering effects in man. All apoB-containing lipoproteins, i.e. VLDL, LDL, Lp(a), are reduced by 25-30%. LÄS MER
12. Atherosclerosis in middle-aged men. A prospective study with focus on factors related to the metabolic syndrome
Sammanfattning : The metabolic syndrome (MetS) is a clustering of cardiovascular disease CVD) risk factors. Pro-spective studies have demonstrated that patients with MetS are about three times more likely to experience CVD events than those without MetS. Up to one third of the adult population seems to be affected worldwide. LÄS MER
13. Protective Immunity in Atherosclerosis
Sammanfattning : The immune system is a promising target for novel therapies that are aiming at reducing cardiovascular diseases. Autoimmune responses against modified low density lipoprotein (LDL) are believed to promote development of atherosclerosis. Proinflammatory immune responses can be counterbalanced by immunosuppressive regulatory T cells (Tregs). LÄS MER
14. Development of a Passive Immunization Strategy Against Atherosclerosis
Sammanfattning : Atherosclerosis is a chronic inflammatory disease, characterized by the accumulation of lipids and fibrous tissue in the wall of medium and large-sized arteries. The characteristic culprit of the disease is the atheroma, or atherosclerotic plaque, a patchy thickening of the arterial wall which affects the lumen, inducing various degrees of stenosis. LÄS MER
15. Myocardial creatine metabolism in experimental infarction and heart failure
Sammanfattning : The failing heart is characterized by changes in structure, function and metabolism. All these changes are usually defined as pathologic remodelling. An important part of this negative remodelling process is disturbances in the myocardial energy metabolism. LÄS MER