Sökning: "Antiparasitic"

Hittade 5 avhandlingar innehållade ordet Antiparasitic.

  1. 1. SARs for the Antiparasitic Plant metabolite Pulchrol

    Författare :Paola Terrazas Villarroel; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; pulchrol; pulchral; SARs; antiparasitic; Leishmania braziliensis; Leishmania amazonensis; Trypanozoma cruzi; Bourreria pulchra; Leishmaniasis; Chagas disease; Synthesis; Pharmacophore; ADMET;

    Sammanfattning : Pulchrol, a natural compound isolated from the roots of the vegetal specie Bourreria pulchra has been shown to possess potential antiparasitic activity toward Trypanosomatids, particularly against Trypanosoma cruzi, which causes the Chagas disease; and moderately against Leishmania species, responsible for Leishmaniasis. In this investigation, several pulchrol analogues were prepared and assayed toward T. LÄS MER

  2. 2. Antiparasitic metabolites from plants used in the Tacana Bolivian native tribe : Traditional medicine, an overview of natural products with medicinal interest

    Författare :Ivan Limachi; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Tacana Traditional Medicine; Antiparasitic; cytotoxicity; Hyptis brevipes; hyptis mutabilis; Tessaria integrifolia; Trichilia adolfi;

    Sammanfattning : The thesis aims to contribute to the preservation of traditional medicinal knowledge of the Tacana Bolivian native tribe, as well as to the isolation and characterization of antiparasitic metabolites from plants used for the treatment of endemic diseases. A selection of medicinal plants, made in collaboration with the Tacana communities who decided which plants have a specific medicinal propose, were collected and identified by the national herbarium of Bolivia, and confirmed by healers from the most representative communities. LÄS MER

  3. 3. Gastrointestinal parasites in pigs : prevalence, risk factors and control

    Författare :Emelie Pettersson; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Gastrointestinal parasites are common in pigs worldwide, and in all production types. Clinical disease is rare and mainly associated with heavy nematode infections, or piglets infected with the coccidia Cystoisospora suis. Subclinical infections are more common and may result in reduced growth and poor feed utilisation. LÄS MER

  4. 4. Oral eflornithine treatment of late-stage human African trypanosomiasis

    Författare :Mikael Boberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sleeping Sickness; Neglected Tropical Diseases; Enantiomers; Nonlinear Mixed Effects Modeling; Pharmacokinetics; Pharmacodynamics;

    Sammanfattning : Human African trypanosomiasis is a fatal disease unless treated. It is a parasitic vector borne disease endemic in sub-Saharan African countries. Eflornithine is a recommended treatment for gambiense human African trypanosomiasis (g-HAT) in the later disease stage when the parasites have infected the central nervous system. LÄS MER

  5. 5. Exploration of factors that influence Plasmodium falciparum fitness and virulence

    Författare :Madle Sirel; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Malaria is an ancient disease that still has profound impact on human population. The virulence of the most lethal malaria parasite, Plasmodium falciparum, can be attributed to several features of the parasite. P. falciparum is known for its indiscriminate red blood cell (RBC) invasion and aptitude for cytoadherence. LÄS MER