Sökning: "Antimicrobial peptides"

Visar resultat 16 - 20 av 126 avhandlingar innehållade orden Antimicrobial peptides.

1. 16. Antibacterial materials for wound care applications utilizing antimicrobial peptides

   Författare :Edvin Blomstrand; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; self-assembly; lyotropic liquid crystals; antibacterial surface; Antimicrobial peptides; Pluronic F-127; hydrogels;

   Sammanfattning : The spread of antibiotic resistance among bacteria has shown that the development of alternative treatments of infections is of vital importance. This thesis has looked at one potential candidate, antimicrobial peptides (AMPs), as an alternative or compliment to traditional antibiotics. LÄS MER

3. 17. Amphiphilic hydrogels functionalized with antimicrobial peptides for wound care

   Författare :Edvin Blomstrand; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; infections; Antimicrobial peptides; hydrogels; wound care; lyotropic liquid crystals; antibacterial surfaces; amphiphilic polymers; surface functionalization;

   Sammanfattning : Bacteria have the potential to cause significant harm to us when found in places where we do not want them, such as in wounds. Through the last century, the gold standard of eradicating bacteria in these cases has been with antibiotics. LÄS MER

4. 18. Relish and the Regulation of Antimicrobial Peptides in Drosophila melanogaster

   Författare :Marika Hedengren Olcott; Barbara Taylor; Jean-Marc Reichhart; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila immunity; NF-kappaB; Relish; antimicrobial peptides; Developmental biology; Utvecklingsbiologi;

   Sammanfattning : The fruit fly Drosophila melanogaster has been a powerful model system in which to study the immune response. When microorganisms breach the mechanical barrier of the insect, phagocytosing cells and a battery of induced antimicrobial molecules rapidly attack them. These antimicrobial peptides can reach micromolar concentrations within a few hours. LÄS MER

5. 19. Mechanisms and Biological Costs of Bacterial Resistance to Antimicrobial Peptides

   Författare :Hava Lofton Tomenius; Dan I Andersson; Ørjan Samuelsen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial peptides; antibiotic resistance; fitness cost; Salmonella Typhimurium; Staphylococcus aureus; bile; serum; pH response; growth rate; mice; phoP; pmrB; waaY; LPS; LL-37; defensins; membrane potential; Mikrobiologi; Microbiology;

   Sammanfattning : The global increasing problem of antibiotic resistance necessarily drives the pursuit and discovery of new antimicrobial agents. Antimicrobial peptides (AMPs) initially seemed like promising new drug candidates. Already members of the innate immune system, it was assumed that they would be bioactive and non-toxic. LÄS MER

7. 20. Interaction Between Antimicrobial Peptides and Phospholipid Membranes : Effects of Peptide Length and Composition

   Författare :Lovisa Ringstad; Martin Malmsten; Per Hansson; Jeremy Ramsden; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adsorption; antibacterial; antimicrobial peptide; bilayer; ellipsometry; electrochemistry; electrostatic interactions; hydrophobicity; liposome; membrane; monolayer; phospholipid; secondary structure; supported bilayer.; PHARMACY; FARMACI; Pharmaceutical Physical Chemistry; farmaceutisk fysikalisk kemi;

   Sammanfattning : Due to increasing problems with bacterial resistance development, there is a growing need for identifying new types of antibiotics. Antimicrobial peptides constitute an interesting group of substances for this purpose, since they are believed to act mainly by disrupting the bacterial membrane, which is a fast and non-specific mechanism. LÄS MER