Sökning: "Antigen processing"
Visar resultat 16 - 20 av 81 avhandlingar innehållade orden Antigen processing.
16. CD8+ T cell specificity in thymic selection and in the recognition of antigen
Sammanfattning : Specificity mediated by the T cell receptor (TCR) is of fundamental importance for the ability of T cells to function, and regulate humoral immunity and effector mechanisms of the innate immune system. T cells recognize composite molecules consisting of products of the major histocompatibility complex (MHC) class I or class 11 loci, in complex with a short peptide fragment derived from endogenous or antigenic proteins. LÄS MER
17. Evaluating antitumoral lymphocytes for adoptive cell therapy : oxidative stress, neoantigen processing and co-stimulation
Sammanfattning : Rapid advancement in the field of immunotherapy has changed the treatment landscape of cancer, especially with the approval of immune checkpoint inhibitors for a wide range of cancer types. However, a large proportion of patients does not benefit from this treatment. LÄS MER
18. A New Look into Protein C Inhibitor : Posttranslational Modifications and their Functions
Sammanfattning : The influences of posttranslational modifications on the functions of the versatile serpin protein C inhibitor (PCI) were studied. PCI is a serine protease inhibitor that is expressed in many tissues and secreted to various fluids in human, including blood plasma, seminal plasma, and urine. LÄS MER
19. Cancer imaging and image analysis methods in whole-body MRI and PET/MRI
Sammanfattning : Diagnostic medical imaging techniques such as magnetic resonance imaging (MRI) and positron emission tomography (PET) can provide structural and functional assessments of the whole body. This has great value for potentially systemic diseases such as cancer. LÄS MER
20. The interactome of the Epstein-Barr virus nuclear antigen 5 suggests novel roles in RNA and protein metabolism
Sammanfattning : Epstein-Barr virus (EBV) is a human herpes virus that infects B and epithelial cells of the oropharynx. EBV is transmitted by saliva and establishes a lifelong latency in over 90% of the world's population. During latency, the virus exists predominantly as multicopy episomes in the nuclei of memory B cells. LÄS MER