Sökning: "Anti-VEGF treatment"
Visar resultat 1 - 5 av 13 avhandlingar innehållade orden Anti-VEGF treatment.
1. Anti-VEGF treatment of patients with diabetic macular edema : Studies of visual acuity, macular edema and patient-reported outcomes
Sammanfattning : The aim of this thesis was to describe and evaluate visual acuity, macular edema and patientreported outcomes (PRO) following anti-VEGF treatment of diabetic macular edema (DME) patients in a real-world setting. Using a longitudinal study design, a cohort of DME patients was followed from baseline to 1 year after treatment start. LÄS MER
2. Patient-reported and medical outcomes in patients treated for diabetic macular edema : A real-world longitudinal study
Sammanfattning : Background Diabetes mellitus can lead to complications, when the complication affects the eyes it is called retinopathy. This can affect the macula and lead to severe loss of vision, diabetic macular edema (DME). This condition has traditionally been treated with laser. LÄS MER
3. Novel Treatment Modalities for High-Risk Neuroblastoma : Studies in Animal Models
Sammanfattning : Neuroblastoma, the most common extracranial solid tumor of childhood, is a heterogeneous tumor. In some patients, the tumor can go into spontaneous regression and disappear whereas other patients have rapidly growing tumors with a poor prognosis. LÄS MER
4. VEGF-mediated vascular functions in health and disease
Sammanfattning : Angiogenesis is essential for physiological processes including embryonic development, tissue regeneration, and reproduction. Under various pathological conditions the same angiogenic process contribute to the onset, development, and progression of many human diseases including cancer, diabetic complications, ocular disease, chronic inflammation and cardiovascular disease. LÄS MER
5. Combination Therapies Targeting PDGF and VEGF Signaling Pathways in Solid Tumors
Sammanfattning : Vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) are independently involved in several cancer-associated mechanisms including autocrine stimulation of cancer cells, stimulation of tumor angiogenesis and regulation of interstitial fluid pressure (IFP). The scope of this thesis was to investigate the combinatory effect of anti-VEGF and anti-PDGF treatment on tumor angiogenesis and tumor IFP. LÄS MER