Sökning: "Annika karolinska institutet"
Visar resultat 1 - 5 av 44 avhandlingar innehållade orden Annika karolinska institutet.
1. Care for elderly : a challenge in the anaesthesia context
Sammanfattning : Anaesthesia care involves bioscience and technical knowledge. Provision of anaesthesia care for elderly surgical patients can be a significant challenge when promoting patient comfort, safety, and satisfaction in a high-tech context with time constraints. LÄS MER
2. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on vitamin A storage in rat hepatic stellate cells
Sammanfattning : The polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs), popularly called dioxins, are persistent pollutants with widespread occurrence in the environment as well as in human food and tissues. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), the most toxic dioxin, as well as other dioxin-like compounds induce a broad spectrum of biochemical and toxic effects, many of which occur at extremely low doses or concentrations. LÄS MER
3. The role of CYP3A4/5 in alprazolam metabolism
Sammanfattning : Cytochrome P450 3A (CYP3A) enzyme family is involved in the metabolism of about 50 % of all drugs in clinical use. Among CYP3A, CYP3A4 and CYP3A5 are the major enzymes in adults; however CYP3A5 is polymorphic and primarily expressed in black populations. LÄS MER
4. Prehospital identification and priority of acute stroke
Sammanfattning : Treatment of acute ischemic stroke is time critical and early initiated reperfusion treatment increases the chances of good recovery. However, in 2007, only 3% of ischemic stroke patients were treated with thrombolysis in Sweden. Patients’ late arrival to hospital was considered to be one of the reasons for the low treatment rate. LÄS MER
5. Cholangiocarcinoma in primary sclerosing cholangitis
Sammanfattning : Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown causes closely associated with ulcerative colitis. PSC is a progressive disease leading to liver failure and need for liver transplantation. Cholangiocarcinoma (CC) occurs in 10-20% of patients with PSC. LÄS MER