Sökning: "Annika Rickle"

Hittade 1 avhandling innehållade orden Annika Rickle.

  1. 1. PTEN and Akt signalling in Alzheimer’s disease

    Författare :Annika Rickle; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :PTEN; Akt; GSK3beta; post-mortem brain; rat primary cortical neurons;

    Sammanfattning : Akt / protein kinase B is an important cell survival kinase that modulates the activity of a range of pro-apoptotic proteins. A major downstream target of Akt is glycogen synthase kinase-3beta (GSK3beta) that phosphorylates the microtubule-associated protein tau. LÄS MER