Sökning: "Annette Theodorsson"
Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Annette Theodorsson.
1. Estrogen-inducible neuropeptides in the rat brain: role in focal ischemic lesions
Sammanfattning : Sex steroids in general and estrogens in particular – in addition to their effects on the reproductive organs – affect a large number of crucial bodily functions, including “higher” brain functions.Neuropeptides constitute the phylogenetically oldest neurotransmitter system and are currently thought to act mainly during stress, disease or injury. LÄS MER
2. Focal ischemic reperfusion stroke model in rats and the role of galanin
Sammanfattning : Stroke is the third most common cause for mortality in industrialised countries and amongst the major causes of long- time morbidity. While the mortality due to myocardial infarction has been dramatically reduced during the last 10-15 years, mortality due to stroke remains almost the same, despite the fact that the two share similar basic pathogenic mechanisms including atherosclerosis, hypertension and diabetes. LÄS MER
3. Challenges in experimental stroke research : The 17β-estradiol example
Sammanfattning : Ischemic stroke causes millions of deaths around the world each year, and surviving patients often suffer from long-term disability. Hundreds of promising drug candidates have been identified in animal models, but the clinical trials have repeatedly failed. Lack of methodological quality in the animal studies, e.g. LÄS MER
4. The dose-dependent effects of estrogens on ischemic stroke
Sammanfattning : Estrogens are a group of female sex hormones that in addition to central roles in reproductive functions also have profound impact on for example brain development, blood vessels, bone tissue, metabolism and the immune system. The dominant endogenous production sites for estrogens in females are the ovaries and adipose tissue, while exogenous sources include combined contraceptive hormone treatments and menopausal hormone therapy. LÄS MER
5. Stress : Clinical and Developmental Aspects of Salivary Cortisol in Infants
Sammanfattning : A functional stress-response system is essential for survival at birth, as well as for health and further development. Altered cortisol response and hypothalamic-pituitary-adrenal system function may have both short and long-term effects on health and development throughout life. Cortisol secretion follows a circadian rhythm in adults. LÄS MER