Sökning: "Anne Beskow"

Hittade 1 avhandling innehållade orden Anne Beskow.

  1. 1. The Path to Destruction : Understanding the mechanism and regulation of proteasomal degradation

    Detta är en avhandling från Stockholm : Department of Molecular Biology and Functional Genomics, Stockholm University

    Författare :Anne Beskow; Stockholms universitet.; [2011]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Proteasome; ubiquitin; p97; Cnc-C; transcription factors; Nrf1; Nrf2; Molecular Biology; molekylärbiologi;

    Sammanfattning : A majority of intracellular proteins are degraded by the ubiquitin proteasome system (UPS). In this thesis, both the mechanism of the degradation and the regulation of UPS have been investigated. The importance of the p97 ATPase for proteasomal degradation of cytosolic substrates was examined. LÄS MER