Sökning: "Anna-lena Lindberg"

Hittade 1 avhandling innehållade orden Anna-lena Lindberg.

  1. 1. Factors influencing the metabolism of inorganic arsenic in humans

    Detta är en avhandling från Stockholm : Karolinska Institutet, Institute of Enviromental Medicine

    Författare :Anna-Lena Lindberg; Karolinska Institutet.; Karolinska Institutet.; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Arsenic; AS3MT; Gender differences; GSTO1; Metabolism; Methylation; MTHFR; Nutrition; Polymorphisms;

    Sammanfattning : p>Inorganic arsenic (iAs), a naturally occurring drinking water contaminant, is a potent human carcinogen and toxicant. It is believed that in humans, as well as in most mammals, inorganic arsenic is biotransformed via reduction and methylation using one-carbon metabolism with S-adenosyl methionine (SAM) as methyl donor, and is excreted mainly in urine as dimethylarsinate (DMA) and methylarsonate (MA) as well as some unmethylated iAs (arsenate (As(V)) and arsenite (As(III)). LÄS MER