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1. 1. Born too small or too early : effects on blood pressure, renal function and retinal vascularization in adulthood : experimental and clinical studies

   Författare :Anna Kistner; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Prenatal dexamethasone; SGA; preterm birth; glomerular filtration rate; ambulatory blood pressure; retinal vascularization; IGF-I; IGFBP-1; metabolic serum markers;

   Sammanfattning : Background: Several epidemiological studies the past fifteen years have suggested a connection between fetal growth retardation and later effects on adult health, such as an increased arterial blood pressure and type 2 diabetes mellitus. We studied the effects of fetal growth retardation in an experimental model were pregnant rats where given the synthetic glucocorticoid dexamethasone (DEX). LÄS MER