Sökning: "Ann-charlotte Bergh"

Hittade 1 avhandling innehållade orden Ann-charlotte Bergh.

1. 1. Importance of microenvironment and antigen in the regulation of growth and survival of CLL cells

   Författare :Ann-Charlotte Bergh; Anders Rosén; Richard Rosenquist Brandell; Dimitar Efremov; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Chronic lymphocytic leukemia (CLL) cells rapidly die when put in culture implying that microenvironmental signals delivered by accessory cells confer CLL cells with a growth advantage. Recent findings show that CLL cells are antigen experienced and antigen binding play a critical role in the pathogenesis of the disease. LÄS MER