Sökning: "Anita Hansson"

Hittade 2 avhandlingar innehållade orden Anita Hansson.

  1. 1. Gluco- and mineralocorticoid receptor regulation of regional brain neurotrophism

    Författare :Anita Christiane Hansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Neurotrophins; BDNF; NT-3; bFGF; FGF receptor; immediate early genes; c-fos; antisense oligodeoxynucleotides; adrenalectomy; stress; glucocorticoids; mineralocorticoids; glucocorticoid receptor; mineralocorticoid; receptor in situ hybridization.;

    Sammanfattning : Gluco- and mineralocorticoid hormones exert powerful actions on brain function and are important in the mediation of the stress response and the survival of hippocampal neurons. The aim of this thesis was to study the influence of glucocorticoid (GR)/mineralocorticoid receptor (MR) actions on brain neurotrophism including analyses of immediate early genes (IEGs) and of feedback responses on GR and/or MR. LÄS MER

  3. 2. Molecular Adaptations in the Endogenous Opioid System in Human and Rodent Brain

    Författare :Muhammad Zubair Hussain; Georgy Bakalkin; Anita Hansson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endogenous Opioid System; Dynorphins; Lateralization; Alcohol Dependence; Emotions; Traumatic Brain Injury; Anterior Cingulate Cortex; Dorsal Striatum; Neuroscience; Neurovetenskap;

    Sammanfattning : The aims of the thesis were to examine i) whether the endogenous opioid system (EOS) is lateralized in human brain areas involved in processing of emotions and pain; ii) whether EOS responses to unilateral brain injury depend on side of lesion, and iii) whether in human alcoholics, this system is involved in molecular adaptations in brain areas relevant for cognitive control of addictive behavior and habit formation.The main findings were that (1) opioid peptides but not opioid receptors and classic neurotransmitters are markedly lateralized in the anterior cingulate cortex involved in processing of  positive and negative emotions and affective component of pain. LÄS MER