Sökning: "Androgen"
Visar resultat 16 - 20 av 215 avhandlingar innehållade ordet Androgen.
16. A step forward in using QSARs for regulatory hazard and exposure assessment of chemicals
Sammanfattning : According to the REACH regulation chemicals produced or imported to the European Union need to be assessed to manage the risk of potential hazard to human health and the environment. An increasing number of chemicals in commerce prompts the need for utilizing faster and cheaper alternative methods for this assessment, such as quantitative structure-activity or property relationships (QSARs or QSPRs). LÄS MER
17. Hormonal Regulation of the Human CYP27A1 and CYP7B1 Genes
Sammanfattning : CYP27A1 and CYP7B1 are widely expressed in various human tissues and are two key enzymes involved in the pathways for conversion of cholesterol to bile acids. Also, CYP27A1 is involved in bioactivation of vitamin D3 and CYP7B1 plays a role in 7alpha-hydroxylation of dehydroepiandrosterone and other steroids. LÄS MER
18. Studies of androgen receptor gene mutations in patients phenotypically ranging from complete androgen insensitivity to men with preserved fertility
Sammanfattning : The androgen insensitivity syndrome (AIS) is the single most common cause of male pseudohermaphroditism, i. e., deficient masculinization which is not explained by disturbed testis development. In its most severe form it affects at least 1/20 000 newborn 46, XY males. LÄS MER
19. Impact of androgen action on reproduction and cardiovascular disease in male cancer survivors
Sammanfattning : .... LÄS MER
20. The role of the prostate in androgen metabolism
Sammanfattning : The androgenic steroid hormones are essential for the physiological development of the prostate gland and are also implicated in pathological processes such as benign prostatic hyperplasia and prostate cancer. The systemic effect of endocrine activity in the prostate gland has so far been considered of minor importance. LÄS MER