Sökning: "Andreas Tjärnberg"

Hittade 2 avhandlingar innehållade orden Andreas Tjärnberg.

1. 1. Exploring the Boundaries of Gene Regulatory Network Inference

   Författare :Andreas Tjärnberg; Erik Sonnhammer; Richard Bonneau; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; GRN; gene regulatory network; network inference; signal to noise ratio; model selection; variable selection; data properties; reverse engineering; ordinary differential equations; gene networks; linear regression; lasso; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

   Sammanfattning : To understand how the components of a complex system like the biological cell interact and regulate each other, we need to collect data for how the components respond to system perturbations. Such data can then be used to solve the inverse problem of inferring a network that describes how the pieces influence each other. LÄS MER

3. 2. High Confidence Network Predictions from Big Biological Data

   Författare :Rasmus Magnusson; Mika Gustafsson; Elin Nyman; Andreas Tjärnberg; Jan Komorowski; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : Biology functions in a most intriguing fashion, with human cells being regulated by multiplex networks of proteins and their dependent systems that control everything from proliferation to cell death. Notably, there are cases when these networks fail to function properly. LÄS MER