Sökning: "Andreas Ejdesjö"

Hittade 2 avhandlingar innehållade orden Andreas Ejdesjö.

1. 1. Genetic predisposition for malformations in diabetic rat pregnancy

   Författare :Andreas Ejdesjö; Ulf J Eriksson; Parri Wentzel; Ted Ebendal; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical cell biology; Medicinsk cellbiologi;

   Sammanfattning : .... LÄS MER

3. 2. Teratogenic Predisposition in Diabetic Rat Pregnancy

   Författare :Andreas Ejdesjö; Ulf J Eriksson; Parri Wentzel; Niklas Nordquist; Gernot Desoye; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetes; malformations; teratogenic; advanced glycation end products; AGE; RAGE; oxidative stress; ROS; gene expression; Medical Cell Biology; Medicinsk cellbiologi;

   Sammanfattning : Pre-gestational diabetes increases the risk of congenital malformation in the offspring and both morbidity and mortality in the diabetic mother and her offspring. During pregnancy, high glucose levels act as a teratogen through several cellular and biochemical pathways and increased production of reactive oxygen species (ROS) has a central role in diabetic embryopathy. LÄS MER