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Visar resultat 1 - 5 av 7 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Microscale Tools for Sample Preparation, Separation and Detection of Neuropeptides

   Författare :Andreas Dahlin; Jonas Bergquist; Karin E. Markides; Robert T. Kennedy; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; Neuropeptides; Microchip; Enhanced microdialysis; Poly dimethylsiloxane PDMS ; Electrospray ionization ESI ; Multidimensional separation; Electrochemical manipulation; Mass spectrometry MS ; Capillary electrophoresis CE ; Microdevice; Microfabrication; Micro total analysis system μ-TAS ; Analytisk kemi; Analytical chemistry; Analytisk kemi;

   Sammanfattning : The analysis of low abundant biological molecules is often challenging due to their chemical properties, low concentration and limited sample volumes. Neuropeptides are one group of molecules that fits these criteria. Neuropeptides also play an important role in biological functions, which makes them extra interesting to analyze. LÄS MER

3. 2. Nanoplasmonic Biosensors compatible with Artificial Cell Membranes

   Författare :Andreas Dahlin; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; gold; colloidal lithography; optical spectroscopy; membrane; lipid bilayer; quartz crystal microbalance; nanofabrication; biosensor; localized surface plasmon resonance; vesicle;

   Sammanfattning : Within life science, there is currently an intense search for novel techniques that enable efficient and reliable analysis of biomolecular interactions. Such methods have future applications within medical diagnostics and drug development, as well as within proteomic research in general. LÄS MER

4. 3. Microdialysis Sampling of Macro Molecules : Fluid Characteristics, Extraction Efficiency and Enhanced Performance

   Författare :Jiangtao Chu; Andreas Dahlin; Klas Hjort; Jan Kehr; Uppsala universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; microdialysis; high molecular weight cut-off; fluid characteristics; fluid recovery; extraction efficiency; biomarker; microporous membrane; macromolecule transport; transmembrane; large pore; surface modification; pluronic; dextran; in vitro; microdialysis catheter; Teknisk fysik med inriktning mot mikrosystemteknik; Engineering Science with specialization in Microsystems Technology; Teknisk fysik med inriktning mot materialvetenskap; Engineering Science with specialization in Materials Science;

   Sammanfattning : In this thesis, fluid characteristics and sampling efficiency of high molecular weight cut-off microdialysis are presented, with the aim of improving the understanding of microdialysis sampling mechanisms and its performance regarding extraction efficiency of biological fluid and biomarkers.Microdialysis is a well-established clinical sampling tool for monitoring small biomarkers such as lactate and glucose. LÄS MER

5. 4. Clinical and experimental studies of bone substitutes and dental implants in compromised bone sites

   Författare :Amela Trbakovic; Andreas Thor; Patricia Hedenqvist; Christer Dahlin; Uppsala universitet; []
   Nyckelord :clinical follow-up; calcium phosphates; rabbit model; sinus lift; radius model; in vivo; bisphosphonates; narrow diameter implants; dental implants; Oral and Maxillofacial Surgery; Käkkirurgi;

   Sammanfattning : Background: With an ageing population, an increase of more challenging implant treatments is expected. In this thesis, we evaluate the outcome of two faster implant protocols, in patients with compromised alveolar bone. LÄS MER

7. 5. Characterization of Molecular Adsorption Using Liquid Chromatography and Mass Spectrometry

   Författare :Torgny Undin; Andreas Dahlin; Sara Bergström Lind; Jonas Bergquist; Elsa Lundanes; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

   Sammanfattning : Molecular adsorption is a key feature in several disciplines of chemistry, covering as diverse fields as chromatographic separation to biomaterial development. This thesis aims at developing methods and techniques for the characterization of molecular adsorption at the liquid-solid interface. LÄS MER