Sökning: "Andrés Aguilera"

Hittade 2 avhandlingar innehållade orden Andrés Aguilera.

  1. 1. The RNA exosome and the maintenance of genome integrity

    Författare :Judit Domingo Prim; Neus Visa; Andrés Aguilera; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; EXOSC10; RRP6; DNA damage; diRNA; DDRNA; DNA end resection; homologous recombination; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : The RNA exosome is a ribonucleolytic complex that acts on different RNA substrates and plays important roles in RNA metabolism. In recent years, the synthesis and the processing of RNA have been directly linked to the integrity of the genome. LÄS MER

  3. 2. Transcription Associated Recombination in Mammalian Cells

    Författare :Linda Savolainen; Thomas Helleday; Andres Aguilera; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; Biologi; molekylärgenetik; Molecular Genetics;

    Sammanfattning : There is increasing evidence that the movement of the transcription machinery through DNA has profound effects on the genomic stability. One such example is a phenomenon known as Transcription Associated Recombination (TAR). Transcription enhances recombination levels to a high degree in all organisms studied, from bacteria to mammals. LÄS MER