Sökning: "André Vicente"

Hittade 1 avhandling innehållade orden André Vicente.

  1. 1. Aniridia-related keratopathy structural changes, signaling pathways and clinical aspects

    Detta är en avhandling från Umeå : Umeå University

    Författare :André Vicente; Umeå universitet.; [2019]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aniridia; aniridia-related keratopathy; PAX6; keratoplasty; fetal cornea; Notch1; Wnt; sonic hedgehog; mTOR; keratocyte; oftalmiatrik; ophthalmology;

    Sammanfattning : Aniridia is a congenital autosomal dominant, bilateral, panocular condition, caused by haploinsufficiency of the Pax6 transcription factor. Aniridia-related keratopathy (ARK) significantly affects vision and quality of life in these patients. LÄS MER