Sökning: "André Gerber"

Hittade 1 avhandling innehållade orden André Gerber.

1. 1. Regulation of RNA Editing : The impact of inosine on the neuronal transcriptome

   Författare :Mikaela Behm; Marie Öhman; André Gerber; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA editing; ADAR; miRNA; Neuron; Brain development; Synapse; Molecular Biology; molekylärbiologi;

   Sammanfattning : The transcriptome of the mammalian brain is extensively modified by adenosine to inosine (A-to-I) nucleotide conversion by two adenosine deaminases (ADAR1 and ADAR2). As adenosine and inosine have different base pairing properties, A-to-I RNA editing shapes the functional output of both coding and non-coding RNAs (ncRNAs) in the brain. LÄS MER