Sökning: "Anders Sköld"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden Anders Sköld.

  1. 1. Computational Modeling of the AT2 Receptor and AT2 Receptor Ligands : Investigating Ligand Binding, Structure–Activity Relationships, and Receptor-Bound Models

    Författare :Christian Sköld; Anders Karlén; Anders Hallberg; Torbjörn Lundstedt; Tommy Liljefors; Uppsala universitet; []
    Nyckelord :Pharmaceutical chemistry; Angiotensin II; AT1; AT2; SAR; bioactive conformation; turn mimetic; peptidomimetic; DISCO; homology model; 3D-QSAR; CoMFA; Farmaceutisk kemi;

    Sammanfattning : Rational conversion of biologically active peptides to nonpeptide compounds with retained activity is an appealing approach in drug development. One important objective of the work presented in this thesis was to use computational modeling to aid in such a conversion of the peptide angiotensin II (Ang II, Asp-Arg-Val-Tyr-Ile-His-Pro-Phe). LÄS MER

  2. 2. T cells in chronic obstructive pulmonary disease

    Författare :Ester Roos-Engstrand; Anders Blomberg; Anders Bucht; Annelie F Behndig; Magnus Sköld; Claes-Göran Löfdahl; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; airway epithelium; bronchoscopy; bronchoalveolar lavage; endobronchial mucosal biopsies; inflammation; flow cytometry; T lymphocytes; CD25; CD127; FoxP3; Lung diseases; Lungsjukdomar; lungmedicin; Lung Medicine;

    Sammanfattning : Background: Tobacco smoking is the main cause of chronic obstructive pulmonary disease, COPD, but the mechanisms by which cigarette smoke induces COPD are still elusive. T lymphocytes have been implicated in the pathogenesis of the disease, but their role in the airway inflammation in COPD is not fully understood. LÄS MER

  3. 3. Integrative Analyses of Perception and Reaction to Information and Warning Sounds in Vehicles

    Författare :Anders Sköld; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Methods; Emotions; Physiological reactions; Mediation; Auditory Icons; Auditory Alerts; Sound Quality; MDU;

    Sammanfattning : The aim of the present thesis is to establish procedures to connect different types of data on auditory perception. This knowledge will lead to both a better understanding of perception in general, but also more efficient and cost effective methods for analyzing auditory perception data. LÄS MER

  4. 4. Perceived character and quality of vehicle sound

    Författare :Anders Sköld; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : .... LÄS MER

  5. 5. Matti Aikio - verk og virke

    Författare :Gunnar Hauk Gjengset; Anders Pettersson; Peter Sköld; Satu Gröndahl; Umeå universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; hybridity; indigenous culture; cross-cultural contacts and conflicts; Sami self-esteem; post-colonial analysis; samisk forfatter; postkolial lesemåte; Literature; Litteraturvetenskap; Literature; litteraturvetenskap;

    Sammanfattning : Denne avhandlingen studerer de litterære verkene til den samiske forfatteren Matti Aikio, samt det nedslag hans verk hadde i samtidens Norge. Aikios romaner, artikler, skuespill og billedkunst ble skapt i tidsrommet 1904-29, en periode da Norge som ny selvstendig nasjonalstat hadde begrenset toleranse med sin samiske minoritet. LÄS MER