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  1. 1. Hypoxia inducible factor-1α in renal cell carcinoma

    Författare :Anders Lidgren; Börje Ljungberg; Torgny Rasmuson; Kjell Grankvist; Anders Bergh; Per-Uno Malmström; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; renal cell carcinoma; hypoxia; RT-PCR; angiogenesis; western blot; tissue microarray; protein; mRNA; HIF-1 alpha; GLUT-1; survival; Urology and andrology; Urologi och andrologi;

    Sammanfattning : Hypoxia Inducible Factor-1α in Renal Cell Carcinoma Departments of Surgical and Perioperative Sciences, Urology and Andrology; Radiation Sciences, Oncology; Medical Biosciences, Pathology; and Medical Biosciences, Clinical Chemistry, Umeå University, Umeå, Sweden Background: Renal cell carcinoma (RCC) accounts for approximately 2-3% of all human cancers. A distinguished feature of RCC is vascularisation and among the three dominating RCC types conventional RCC (cRCC) generally is more vascularised than papillary RCC (pRCC) and chromophobe RCC (chRCC). LÄS MER