Sökning: "Anca-associated vasculitis"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden Anca-associated vasculitis.

1. 1. Clinical and epidemiological Studies in ANCA-associated vasculitis

   Författare :Jens Rathmann; Reumatologi och molekylär skelettbiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vasculitis; ANCA vasculitis; Epidemiologi; Infection; Classification;

   Sammanfattning : Objectives:This thesis aims to provide an overview of the epidemiology of AAV in southern Sweden, to evaluate different classification criteria in AAV. In addition we study if infection is a risk factor for later development of AAV comparing patients with AAV with a matched population cohort and to examine the occurrence of severe infections as an outcome in AAV. LÄS MER

3. 2. Long-term follow-up of patients with ANCA-associated vasculitis

   Författare :Caroline Heijl; Njurmedicin; []
   Nyckelord :Anca-associated vasculitis;

   Sammanfattning : This thesis is based on long-term follow-up results from two cohorts of patients with ANCA-associated vasculitis; one cohort with 535 patients originally included in 4 European randomized clinical trials (papers I and II) and one Swedish population-based cohort including 195 patients (papers III and IV). Two areas are covered in the two cohorts, respectively; the assessment of mortality, prognostic factors and causes of death in the two cohorts (paper I and III) and the assessment of malignancy risk compared with a matched general population (papers II and IV). LÄS MER

4. 3. Inflammatory biomarkers in ANCA-associated vasculitis

   Författare :Ásta Dögg Jónasdóttir; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Background: Antineutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) is a heterogenous group of relatively rare and serious small vessel vasculitides, characterized by the presence of proteinase 3 (PR3) ANCA or myeloperoxidase (MPO) ANCA. The disease manifestations vary widely, from a localized form to a serious disease with multi-organ failure. LÄS MER

5. 4. Macrophages and Neutrophils in ANCA Associated Vasculitis

   Författare :Susanne Ohlsson; Njurmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Autoimmune diseases are diseases where the immune system attacks the body itself. They are commonly complex diseases with no clear aetiology, a fact that complicates treatment and the study of these diseases. LÄS MER

7. 5. The Balance between Pro- and Antiinflammatory Molecules in ANCA-Associated Vasculitis

   Författare :Sophie Ohlsson; Njurmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nephrology; Urologi; nefrologi; Urology; monocyte; SLPI; proteinase 3; ANCA; vasculitis; inflammation;

   Sammanfattning : ANCA-associated systemic vasculitis (AASV) is a group of inflammatory disorders, characterized by inflammation and necrosis of blood vessels and frequently granuloma formation. Patients with AASV make autoantibodies, so called ANCA, against proteins present in the granules of neutrophils and monocytes, mainly proteinase 3 (PR3) and myeloperoxidase (MPO). LÄS MER