Sökning: "Analytical biotechnology"

Visar resultat 1 - 5 av 77 avhandlingar innehållade orden Analytical biotechnology.

  1. 1. Asymmetrical Flow Field-Flow Fractionation in the Application to Biological Macromolecules

    Författare :Cecilia Arfvidsson; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; Analytisk kemi; Bioteknik; Biotechnology; biotechnology; recombinant protein production; molecular weight; Escherichia coli; ribosomes; glutenin; asymmetrical flow field-flow fractionation; multiangle light scattering;

    Sammanfattning : Asymmetrical flow field-flow fractionation (AsFlFFF) is especially useful in the application to biological macromolecules due to the absence of a stationary phase in the separation channel. As a result no upper exclusion limit occurs and low shear forces affect the sample components. LÄS MER

  3. 2. Development of Electroacoustic Sensors for Biomolecular Interaction Analysis

    Författare :Henrik Anderson; Ilia Katardjiev; Björn Ingemarsson; Inger Vikholm-Lundin; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; biosensor; protein interactions; kinetics; affinity; QCM; quartz crystal microbalance; piezoelectric resonators; dissipation; motional resistance; Bioanalytical engineering; Bioanalytisk teknik; Analytical chemistry; Analytisk kemi; Teknisk fysik med inriktning mot mikrosystemteknik; Engineering Science with specialization in Microsystems Technology;

    Sammanfattning : Biomolecular interaction analysis to determine the kinetics and affinity between interacting partners is important for the fundamental understanding of biology, as well as for the development of new pharmaceutical substances. A quartz crystal microbalance instrument suitable for kinetics and affinity analyses of interaction events was developed. LÄS MER

  4. 3. Cell wall chemotyping for functional genomics : applications of pyrolysis-gas chromatography / mass spectrometry

    Författare :Lorenz Gerber; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The interest in lignocellulose as a sustainable resource for energy and materials has fueled research on biotechnology applications in tree breeding to improve biomass production and wood properties. An important aspect of this research is the basic understanding of gene function in wood formation, where analysis of wood chemistry and wood structure is of utmost importance. LÄS MER

  5. 4. Exploring genetic heterogeneity in cancer using high-throughput DNA and RNA sequencing

    Författare :Erik Fasterius; Cristina Al-Khalili Szigyarto; Mathias Uhlén; Peter-Bram ’t Hoen; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Biotechnology; bioinformatics; RNA-seq; WGS; WES; systems biology; variant analysis; single nucleotide variant; gene expression; machine learning; clustering; open source; R; bioconductor; Python; Bioteknologi; Biotechnology;

    Sammanfattning : High-throughput sequencing (HTS) technology has revolutionised the biomedical sciences, where it is used to analyse the genetic makeup and gene expression patterns of both primary patient tissue samples and models cultivated in vitro. This makes it especially useful for research on cancer, a disease that is characterised by its deadliness and genetic heterogeneity. LÄS MER

  7. 5. Optimization of the Sensor-Chip Surface in a Capacitive Biosensor for use in Aflatoxin Assays

    Författare :Alvaro Gutierrez Rojas; Bioteknik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; aflatoxin; biosensor; antibody; bioimprinting; gold nanoparticles; capacitance;

    Sammanfattning : The capacitive biosensor technology can be utilized for the analytical detection of a variety of different compounds. By employing the electrical double-layer principle, it is possible to detect very low concentrations of the target analyte due the methods inherent high sensitivity. LÄS MER