Sökning: "Analytical Pharmaceutical Chemistry"

Visar resultat 11 - 15 av 62 avhandlingar innehållade orden Analytical Pharmaceutical Chemistry.

  1. 11. Microextraction by packed sorbent of drugs and peptides in biological fluids

    Författare :Seyed Mosayeb Daryanavard; Mohamed Abdel-Rehim; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEPS; Local anaesthetics drugs; Peptides; Analytical Chemistry; analytisk kemi; analytisk farmaceutisk kemi; Analytical Pharmaceutical Chemistry;

    Sammanfattning : Sample preparation as the first step in an analytical procedure has an important role, particularly in bioanalysis, because of the complexity of biological samples (blood plasma and urine). Biological matrix such as plasma and blood contains proteins, organic and inorganic salts, acids, bases and various organic compounds with similar chemistry to the analytes of interest. LÄS MER

  3. 12. Studies of Micellar Electrokinetic Chromatography as an Analytical Technique in Pharmaceutical Analysis - an Industrial Perspective

    Författare :Karin Stubberud; Brian J. Clark; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Micellar Electrokinetic Chromatography; Pharmaceutical Analysis; Chemometrics; Validation; Mass Spectrometry; Partial-filling technique; Pilocarpine; Ibuprofen; Codeine.; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi; analytisk farmaceutisk kemi; Analytical Pharmaceutical Chemistry;

    Sammanfattning : Studies have been performed to evaluate the use of micellar electrokinetic chromatography (MEKC), one mode of capillary electrophoresis (CE), as an analytical technique in industrial pharmaceutical analysis. The potential for using chemometrics for the optimisation of MEKC methods has also been studied as well as the possibilities of coupling MEKC with mass spectrometry (MS). LÄS MER

  4. 13. SALDI-MS Method Development for Analysis of Pharmaceuticals and Polymer Degradation Products

    Författare :Nina Aminlashgari; Minna Hakkarainen; Klas Engvall; Åsa Emmer; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Surface assisted laser desorption ionization-mass spectrometry SALDI-MS ; polyester degradation products; pharmaceutical compounds; nanoparticles; nanocomposites.;

    Sammanfattning : Surface assisted laser desorption ionization-mass spectrometry (SALDI-MS) was evaluated as a new tool for analysis of polymer degradation products. A SALDI method was developed enabling rapid analysis of low molecular mass polyesters and their degradation products. LÄS MER

  5. 14. Development of Methods in CE, CE-MS and MS/MS : Applications in Pharmaceutical, Biomedical and Forensic sciences

    Författare :Emmy Jäverfalk-Hoyes; Jonas Bergquist; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi; analytisk farmaceutisk kemi; Analytical Pharmaceutical Chemistry;

    Sammanfattning : Capillary electrophoresis-mass spectrometry has been used successfully for the analysis of a wide range of analytes such as chiral local anaesthetics, sulphonated reactive dyes and endogenous neurotransmitters and neuropeptides.The partial filling technique was used in CE-MS for chiral separation of bupivacaine and ropivacaine using the non-volatile selector β-cyclodextrin. LÄS MER

  7. 15. Heterogeneities in polymer gels: Effects on swelling and mechanical properties

    Författare :Mikael Larsson; Chalmers tekniska högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gel; Phase separation; Heterogeneities; Polyacrylic acid.; HPMC; Glass transition temperature; Microfibrillated cellulose; Filler; Elastomer;

    Sammanfattning : Polymeric hydrogels is a class of scientifically interesting materials that are being extensively studied. They are found in numerous applications within; drug delivery, hygiene products, food industry, analytical chemistry, etc. In addition, polymeric hydrogels have promising future applications as; cell scaffolds, implants, sensors, etc. LÄS MER