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1. 1. Microdialysis and Intensive Care. Clinical and experimental studies

   Författare :Per Ederoth; Anestesiologi och intensivvård; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaesthesiology; traumatic brain injury; glucose; glycerol; lipolysis; epidural; postoperative analgesia; experimental pancreatitis; human; blood-brain barrier; morphine; pharmacokinetics; Microdialysis; intensive care; Anestesiologi; intensivvård;

   Sammanfattning : Microdialysis was used to monitor local concentrations of energy metabolites in different organs, and to study the pharmacokinetics of morphine over the blood-brain barrier in intact and injured brain tissue in conditions treated in the Intensive Care Unit. After major abdominal or thoracoabdominal surgery, postoperative thoracic epidural analgesia resulted in higher glycerol concentrations in the deltoid subcutaneous adipose tissue, implying increased lipolysis, on the third postoperative day as compared to intravenous infusion of morphine, possibly due to a locally increased sympathetic tone. LÄS MER

3. 2. Experiences of abandonment and anonymity among arthroplastic surgery patients in the perioperative period : some issues concerning communication, pain and suffering

   Författare :Mats Sjöling; Kenneth Asplund; Björn Biber; Hans Malker; Björn Sjöström; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaesthesiology and intensive care; Advice; communication; information; nursing; orthopaedic care; pain; suffering; Anestesiologi och intensivvård; Anaesthetics and intensive care; Anestesiologi och intensivvård; Anaesthesiology; anestesiologi;

   Sammanfattning : Det övergripande syftet med avhandlingsarbetet är att illustrera och belysa upplevelsen av att vara patient med behov av ledprotes, avseende aspekterna kommunikation, smärtupplevelse, lidande och tillfredsställelse med vård och behandling. Under väntetiden för ledprotesoperation upplever deltagarna i studierna lidande i olika former, tillika att vården är otillgänglig och onåbar i ett ansiktslöst system (I). LÄS MER

4. 3. The Intensive Care Unit syndrome/delirium, patients' perspective and clinical signs

   Författare :Anetth Granberg Axèll; Anestesiologi och intensivvård; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intensive care; delirium; ICU-syndrome; acute confusion; psychosis; critical care; experiences; sleep-deprivation; sensory overload; sensory underload; Anaesthesiology; environment.; Anestesiologi; intensivvård;

   Sammanfattning : When a person becomes critically ill, injured and/or undergoes major surgery and requires intensive care, a complex dilemma can arise. The condition of the illness, the specific caring situation and the environment lead to significant changes and effects in the senses and perceptional abilities. LÄS MER

5. 4. The epidemiology of risk factors and short- and long-term outcome in the Swedish intensive care cohort

   Författare :Björn Ahlström; Miklós Lipcsey; Ing-Marie Larsson; Gunnar Strandberg; Markus Skrifvars; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Intensive care; Intensive care unit; Sepsis; Covid-19; Epidemiology; Dementia; Mortality; Causes of death; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

   Sammanfattning : The sepsis syndrome is present in ¼ to ⅓ of patients in intensive care units (ICUs) worldwide. The short-term prognosis is grim, with a 30-day mortality of 30–35%; however, the long- term outcomes are now being explored, as multi-professional follow-up after ICU care is increasingly being implemented. LÄS MER

7. 5. Cooling and dopamine

   Författare :Roger Roscher; Anestesiologi och intensivvård; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaesthesiology; electrophysiology; cooling; Hypothermia; swine; lung transplantation; organ preservation; dopamine; circulation; contractility; oxygenation; intensive care; Anestesiologi; intensivvård;

   Sammanfattning : There is little knowledge about the circulatory effects of dopamine in hypothermia. Induced hypothermia has been shown to improve outcome in various settings. Hypothermia is also used for preservation of organs that are harvested for transplantation. LÄS MER