Sökning: "Amyotrophic lateral sclerosis"

Visar resultat 11 - 15 av 86 avhandlingar innehållade orden Amyotrophic lateral sclerosis.

1. 11. Misfolded superoxide dismutase-1 in amyotrophic lateral sclerosis

   Författare :Per Zetterström; Stefan L Marklund; Lawrence J. Hayward; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALS; SOD1; protein misfolding; SOD1 conformation; disulfide-reduced; transgenic mice; cerebrospinal fluid; protein-protein interaction; antibodies; Clinical chemistry; Klinisk kemi; Clinical Chemistry; klinisk kemi;

   Sammanfattning : Amyotrophic lateral sclerosis (ALS) is a disease in which the motor neurons die in a progressive manner, leading to paralysis and muscle wasting. ALS is always fatal, usually through respiratory failure when the disease reaches muscles needed for breathing. Most cases are sporadic, but approximately 5–10% are familial. LÄS MER

3. 12. Biomarkers and psychological stress in amyotrophic lateral sclerosis

   Författare :Ulf Kläppe; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Amyotrophic lateral sclerosis (ALS) is a complex and progressive neurological disorder that causes a wide range of symptoms, including muscle weakness, mobility impairment, and marked functional decline. Unfortunately, there is currently no known cure for ALS, and median survival time is between two to four years, although this varies considerably between individuals. LÄS MER

4. 13. Amyotrophic lateral sclerosis - a study in transgenic mice

   Författare :Hanna Wootz; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; Neurologi;

   Sammanfattning : .... LÄS MER

5. 14. Epidemiologic studies of amytrophic lateral sclerosis

   Författare :Fang Fang; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Amyotrophic lateral sclerosis; association; bone turnover; early life exposure; familial aggregation; incidence; lead exposure; relative risk; temporal trend;

   Sammanfattning : Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder characterized by progressive muscular paralysis reflecting degeneration of motor neurons in the primary motor cortex, corticospinal tracts, brainstem and spinal cord. The causes of ALS remain largely unknown more than 140 years after the disease was first described. LÄS MER

7. 15. Risk factors and amyotrophic lateral sclerosis : an epidemiologic approach

   Författare :Tracy Peters; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Amyotrophic Lateral Sclerosis (ALS) is a debilitating and rare disorder; progressively the patient’s muscles go into paralyses limiting their ability to walk, do day-to-day tasks, and eat. This thesis covers risk factors related to ALS. LÄS MER