Sökning: "Amyloid beta 1-42"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden Amyloid beta 1-42.

  1. 1. The Impact of Amyloid Peptides on Pericytes in Alzheimer's Disease

    Författare :Nina Schultz; Klinisk minnesforskning; []
    Nyckelord :Pericytes; Alzheimer s disease; Amyloid peptides; IAPP; Amyloid beta 1-42; Amyloid beta 1-40; Cell death; NG2; Retina; Hippocampus;

    Sammanfattning : .... LÄS MER

  3. 2. Understanding secondary nucleation of the amyloid β peptide

    Författare :Dev Thacker; NanoLund: Centre for Nanoscience; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Alzheimer s disease AD ; A beta 1-42; Amyloid aggregation; secondary nucleation;

    Sammanfattning : Alzheimer’s Disease (AD) is a devastating neurodegenerative disease associated with massive neuronal cell death during its pathology. The involvement of the amyloid β 42 (Aβ42) peptideand its role in neurotoxicity is now well established. LÄS MER

  4. 3. Alzheimer's Disease: The role of alpha1-antichymotrypsin-amyloid peptide (Abeta 1-42) interaction in the pathogenesis of Alzheimer's disease

    Författare :Yongxin Sun; Lund Obstetrik och gynekologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurofysiologi; neuropsykologi; neurophysiology; Neurologi; neuropsychology; Neurology; lipid metabolism.; inflammation; á1-antichymotrypsin; Alzheimer’s disease; amyloid-â peptide;

    Sammanfattning : Alzheimer?s disease (AD) is an age-related, irreversible brain disorder that occurs gradually and results in memory loss, behavioural and personality changes. The disease is characterized by an abnormal accumulation of amyloid-beta (Ab) peptide in the extracellular space and the protein Tau within nerve cells of certain regions of the brain. LÄS MER

  5. 4. Evaluation of amyloid precursor protein and ß-amyloid as biomarkers for Alzheimer s disease

    Författare :Annika Olsson; Göteborgs universitet; []
    Nyckelord :Alzheimer s disease; amyloid precursor protein; ß-amyloid; biomarker; cerebrospinal fluid; enzyme-linked immunosorbent assay; plasma;

    Sammanfattning : Alzheimer s disease (AD) is a neurodegenerative disorder characterised by accumulations of neurofibrillary tangles and amyloid plaques. The major components of the amyloid deposits are the ß-amyloid (Aß) peptides derived from the amyloid precursor protein (APP). LÄS MER

  7. 5. Developing a Porcine Model to Study the Glymphatic System

    Författare :Nicholas Bechet; Glia-Immune Interactions; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glymphatic system; cerebrospinal fluid; Porcine; in vivo imaging; amyloid beta; Alzheimer disease;

    Sammanfattning : The glymphatic system is a brain-wide solute clearance system that has developed in the brain to clear metabolic waste during sleep. This clearance is mediated by advective fluxes of cerebrospinal fluid (CSF) along perivascular spaces (PVS) and through the brain. LÄS MER