Sökning: "Amel Guenifi"

Hittade 1 avhandling innehållade orden Amel Guenifi.

1. 1. Mechanisms of impaired insulin release in type-2 diabetes : studies in the GK rat model

   Författare :Amel Guenifi; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Goto-Kakizaki GK rat; Type-2 diabetes; insulin secretion; morphometry; adenylyl cyclase AC ; phospholipase-C PLC ; ß-cell;

   Sammanfattning : Type-2 diabetes is a complex syndrome with a polygenic and multifactorial aetiology. It is characterised by its relatively late appearance in life and its mild progressive course. Glucose intolerance can generally be ascribed to disturbed pancreatic hormonal secretion and/or insulin resistance in the liver and extrahepatic tissues. LÄS MER