Sökning: "Amani Eltayb"

Hittade 1 avhandling innehållade orden Amani Eltayb.

1. 1. Experimental studies on novel pharmacological strategies in the treatment of schizophrenia

   Författare :Amani Eltayb; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Schizophrenia; L-dopa; topiramate; 5-HT2C; citalopram; WAY 100635; CAR; catalepsy;

   Sammanfattning : The modified dopamine (DA) hypothesis of schizophrenia suggests a hyperdopaminergic state in subcortical brain regions, which is believed to cause positive symptoms, while cortical regions may show a hypodopaminergic state which is believed to generate negative and cognitive symptoms. Positive symptoms are improved by typical antipsychotic drug (APD) treatment. LÄS MER