Sökning: "Alzheimers sjukdomar"

Visar resultat 1 - 5 av 53 avhandlingar innehållade orden Alzheimers sjukdomar.

  1. 1. Making Death Matter : A Feminist Technoscience Study of Alzheimer's Sciences in the Laboratory

    Författare :Tara Mehrabi; Cecilia Åsberg; Ericka Johnson; Stine Willum Adrian; Linköpings universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; HUMANIORA; HUMANITIES; HUMANIORA; HUMANITIES; HUMANIORA; HUMANITIES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Agential realism; posthumanities; new materialism; feminist technoscience; STS; gender studies; Human Animal Studies; matters of practice; animal experimentation; spectrum of killability; agential asymmetry; Drosophila melanogaster; fruit flies; Alzheimer’s sciences; laboratory ethnography; biological waste; politics of categorization; mattering death; ethics of relationality.; Agentiell realism; posthumaniora; nymaterialism; feministiska teknovetenskpliga studier; genusvetenskap; vetenskapliga praktiker; djurförsök; agentiell assymetri; fruktflugor; Alzheimers sjukdomar; labbetnografi; biologiskt avfall; döden; relationell etik; processontologi; Genusstudier; Cultural Studies; Kulturstudier; History of Ideas; Idé- och lärdomshistoria; Philosophy; Filosofi; Social Sciences Interdisciplinary; Tvärvetenskapliga studier inom samhällsvetenskap;

    Sammanfattning : This thesis is a contribution to feminist laboratory studies and a critical engagement with the natural sciences, or more precisely research on the biochemical workings and deadly relations of Alzheimer’s disease emanating from a year of field work in a Drosophila fly lab. The natural sciences have been a point of fascination within the field of gender studies for decades. LÄS MER

  3. 2. Risk factors for development of neurocognitive disorders

    Författare :Anna-Märta Gustavsson; Klinisk minnesforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vascular risk factors; dementia; Alzheimer’s disease; ß-amyloid; white matter hyperintensities; cerebral small vessel disease;

    Sammanfattning : Vascular risk factors are believed to be involved in dementia development by increasing risk of the most common dementia types, Alzheimer’s disease (AD) and vascular dementia. The aim of this thesis was to study if risk factors affect key brain pathology directly, by using biomarkers for dementia in preclinical stages, and to assess previous findings in a large population-based setting. LÄS MER

  4. 3. Alzheimer's disease and dementia with Lewy bodies: Special focus on the role of serpins

    Författare :Henrietta Nielsen; Enheten för kroniska inflammatoriska och degenerativa sjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Serine protease inhibitors (Serpins) are involved in the pathogenesis of neurodegenerative dementia, including the two most common types, Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB). The pathological characteristics of AD include senile plaques, mainly composed of aggregated amyloid-beta peptide (Abeta1-42), but also serpins, and neurofibrillary tangles of hyperphosphorylated tau protein. LÄS MER

  5. 4. Amyloid Beta – Biotherapy Target and Biotechnological Tool

    Författare :Sebastian W. Meister; Stefan Ståhl; John Löfblom; Maarten Merkx; KTH; []
    Nyckelord :Alzheimer’s disease; amyloid beta; blood-brain barrier; green-fluorescent protein; intracellular assays; proteases; protease substrate specificity; protein aggregation; protein engineering.; Bioteknologi; Biotechnology;

    Sammanfattning : Alzheimer’s disease is a progressive neurodegenerative disease characterized primarily by memory impairment and cognitive decline. As of 2020, an estimated 50 million people suffer from Alzheimer’s disease or related dementia and no disease-modifying treatment options are yet approved for clinical practice. LÄS MER

  7. 5. Markers of Prognosis in Neurodegenerative Dementia

    Författare :Kajsa Stubendorff; Klinisk minnesforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lewy body disease; Alzheimer s disease; dementia with Lewy bodies; prognosis; survival; longitudinal studies; biomarkers; cerebrospinal fluid; dysautonomic orthostatic hypotension; memantine;

    Sammanfattning : Background: A prognostic marker should provide information about course and outcome of disease, e.g. predict time to a given endpoint or rate of progression due to disease in patients or subgroups of patients. Prognostic markers could be targeted to apply during the entire clinical course or just during distinct stages of the disease. LÄS MER