Sökning: "Alves"

Visar resultat 1 - 5 av 14 avhandlingar innehållade ordet Alves.

  1. 1. Mechanisms Underlying the Specification of Definitive Hematopoiesis

    Författare :Rita Alves; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GATA2; mitotic bookmarking; HSC; transcription factors; reprogramming;

    Sammanfattning : Hematopoietic stem cells (HSCs) maintain blood through self-renewal and differentiation. Although HSC transplantation is the only cure for various blood disorders, generating and maintaining HSCs in vitro remains challenging, partly due to a limited understanding of the cellular and molecular mechanisms underlying human HSC ontogeny. LÄS MER

  3. 2. Leveraging Existing Microarchitectural Structures to Improve First-Level Caching Efficiency

    Författare :Ricardo Alves; David Black-Schaffer; Stefanos Kaxiras; Mattan Erez; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Energy Efficient Caching; Memory Architecture; Single Thread Performance; First-Level Caching; Out-of-Order Pipelines; Instruction Scheduling; Filter-Cache; Way-Prediction; Value-Prediction; Register-Sharing.;

    Sammanfattning : Low-latency data access is essential for performance. To achieve this, processors use fast first-level caches combined with out-of-order execution, to decrease and hide memory access latency respectively. LÄS MER

  4. 3. A Never-Ending Thirst: Artistic Reforms to Neoliberal-Teflon Imperviousness

    Författare :André Alves; Göteborgs universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; Neoliberal-Teflon; inscription; picture-making; listening ethics; negative capability; insufficient picture; affectability; co-motion;

    Sammanfattning : This text is the dissertation element of my artistic research project, A Never-Ending Thirst: Artistic Reforms to Neoliberal-Teflon Imperviousness, developed within the doctoral studies program at HDK-Valand—the Academy of Art and Design, University of Gothenburg (2016-2021). Along with documentation of twelve artistic projects that support my practice-based inquiry, this text is submitted in partial fulfilment of the requirement for the Degree of Doctor in the Fine, Applied, and Performing Arts. LÄS MER

  5. 4. Diet and postmenopausal breast cancer - With a focus on low-grade inflammation

    Författare :Joana Alves Dias; Nutritionsepidemiologi; []
    Nyckelord :Oxidative stress; low-grade inflammation; Biomarkers of inflammation; cytokines; ICC; variation; diet; dietary recommendations; diet quality index; food patterns; reduced rank regression; obesity; CVD; postmenopausal breast cancer; epidemiology; cross sectional; nested case-control;

    Sammanfattning : Diet-breast cancer studies have shown that “healthy eating patterns” are associated with decreased risk whereas unhealthy patterns (especially those including alcohol) are associated with increased risk, particularly in postmenopausal women. The potential mechanisms behind the observed associations are still under investigation. LÄS MER

  7. 5. Novel culture systems to model testicular function and organization

    Författare :João Pedro Alves Lopes; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In vitro systems to model the testicular microenvironment are required to study physiology and pathology of the testis, the gonadotoxic effect of environmental and pharmaceutical chemicals, as well as to explore the mechanisms ruling spermatogonial stem cell (SSC) self-renewal and differentiation. The knowledge produced in in vitro experiments, using animal, but most importantly utilizing human models, will contribute to the discovery of safe medical treatments and might provide translational tools to treat male infertility problems. LÄS MER