Sökning: "Alport syndrome"

Hittade 2 avhandlingar innehållade orden Alport syndrome.

1. 1. Type IV collagen : regulation of COL4A1 and COL4A2 genes and gene therapy of Alport syndrome

   Författare :Pirkko Kortteinen; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :adenovirus; Alport syndrome; basement membrane; bidirectional promoter; collagen; gene regulation; gene therapy; promoter analysis; kidney gene transfer; organ perfusion; type IV collagen;

   Sammanfattning : Type IV collagen is an important structural protein in basement membranes, which am thin sheet-like structures located between organized tissues and the connective tissue. Type IV collagen is composed of six genetically different [alpha] chains. LÄS MER

3. 2. Basal lamina genes affected in leiomyomatosis and congenital muscular dystrophy : structure and mutation analyses of the collagen COL4A6 and laminin LAMA2 genes

   Författare :Xu Zhang; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Basal laminae (basement membranes) are flexible thin sheets of specialized extracellular matrix separating organ cells from the underlying or surrounding connective tissues. They are found beneath epithelial and endothelial cells amd surrounding different cells, such as muscle fibers and nerves. LÄS MER