Sökning: "Allylic alcohols"

Visar resultat 1 - 5 av 51 avhandlingar innehållade orden Allylic alcohols.

  1. 1. Allylic alcohols and aziridines from alkenes : Studies in asymmetric catalysis

    Författare :Mikael J. Södergren; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Enantioselective; allylic alcohols; epoxide rearrangement; lithium amides; desymmetrization; kinetic resolution; allylic oxidation; alkenes; aziridination; Kemi; Chemistry; Kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : The development of methodology for asymmetric catalytic transformation of alkenederivatives is summarized. The studies concern the [a] Cu(I)-catalyzed allylic oxidation,[b] isomerization of epoxides to allyl alcohols, and [c] Cu(I)-catalyzed alkeneaziridination, respectively.[a] The preparation of exo-2-azabicyclo[2.2. LÄS MER

  3. 2. Transition metal-catalyzed allylic and vinylic functionalization : Method development and mechanistic investigations

    Författare :Johanna M. Larsson; Kálmán J. Szabó; Dennis G. Hall; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; palladium; copper; catalysis; Heck reaction; C-H functionalization; allylic substitution; silylation; borylation; trifluoromethylation; fluorination; mechanistic study; transition metal; alkene; allylic silane; allylic boronate; allylic fluoride; organisk kemi; Organic Chemistry;

    Sammanfattning : The use of small molecule building blocks in, for example, pharmaceutical research and new material development, creates a need for new and improved organic synthesis methods. The use of transition metals as mediators and catalysts opens up new reaction pathways that have made the synthesis of completely new compounds possible as well as greatly improved the synthetic routes to known compounds. LÄS MER

  4. 3. Transition metal-catalysed isomerisation of allylic alcohols : Applications to C−C, C−F and C−Cl bond formation

    Författare :Nanna Ahlsten; Belén Martín-Matute; M. J. Jonathan Williams; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; transiton metal-catalysis; allylic alcohols; isomerisation; halogenation; organisk kemi; Organic Chemistry;

    Sammanfattning : The focus of this thesis has been to develop selective and atom-economical methods for carbon-carbon and carbon-heteroatom bond formation, and to some extent improve on existing findings in this area. More specifically, methods for the catalytic generation of enolates from allylic alcohols and their in situ functionalisation with electrophilic reagents are described. LÄS MER

  5. 4. Direct Catalytic Nucleophilic Substitution of Non-Derivatized Alcohols

    Författare :Anon Bunrit; Joseph Samec; Joseph Moran; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; nucleophilic substitution; catalysis; alcohols; stereospecific; Lewis acid; Brønsted acid base; bifunctional; heterocycles; organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis focuses on the development of methods for the activation of the hydroxyl group in non-derivatized alcohols in substitution reactions. The thesis is divided into two parts, describing three different catalytic systems. LÄS MER

  7. 5. Ruthenium-catalyzed redox reactions and lipase-catalyzed asymmetric transformations of alcohols

    Författare :Michaela Edin; Jan-E. Bäckvall; Manfred T. Reetz; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ruthenium; lipase; catalysis; alcohols; diols; Chemistry; Kemi;

    Sammanfattning : The major part of this thesis describes the synthesis of enantiopure alcohols and diols by combining ruthenium-catalyzed redox reactions that lead to racemization or epimerization and lipase-catalyzed asymmetric trans-formations in one-pot.A mechanistic study of the unexpected facile formation of meso-diacetate products found in enzyme-catalyzed acetylations of alkanediols with Candida antarctica lipase B (CALB) was first performed. LÄS MER