Sökning: "Allergic rhinitis Histamine challenge"

Hittade 5 avhandlingar innehållade orden Allergic rhinitis Histamine challenge.

1. 1. Experimental and Clinical Studies of SLPI, with Special Reference to IgE-Mediated Allergic Reactions

   Författare :Ulla Westin; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; in situ hybridisation; immunohistochemistry; allergic rhinitis; atopic subjects; IgE-mediated histamine release; mast cell proteases; plasma protease inhibitors; SLPI; human leukocyte proteases; Immunology; serology; transplantation; Immunologi; serologi;

   Sammanfattning : In this study we demonstrated the production of SLPI (Secretory Leukocyte Protease Inhibitor) in serous glands in the nasal mucosa. We have shown that the pattern of the expression of mRNA corresponds to the encoded protein. The encoded protein was detected by immunohistochemical methods and mRNA was discovered by in situ hybridisation. LÄS MER

3. 2. Nasal and bronchial airway reactivity in allergic and non allergic airway inflammation

   Författare :Karl-Gustav Kölbeck; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Nasal hyperreactivity; airway hyperresponsiveness; Rhinostereometry; organic dust; adhesion molecules; endothelial cells;

   Sammanfattning : In allergic or asthmatic airways disease, upper and lower airways show a uniform eosinophilic inflammation of the mucosa, and bronchial hyperreactivity is a common finding. To study the co- variation of mucosal reactivity in upper and lower airways, histamine challenges of both sites were performed in a group of patients with allergic rhinitis during non-season. LÄS MER

4. 3. Rhinostereometry and laser doppler flowmetry : simultaneous measurements of inflammation and steroid effects in normal and allergic human nasal mucosa

   Författare :Hans Grudemo; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Rhinastereometry; Laser Doppler Flowmetry; Nasal mucosa; Allergic rhinitis Histamine challenge;

   Sammanfattning : This thesis describes the development of a combination of non-invasive methods for measuring different aspects of inflammation simultaneously in a selected part of the human nasal mucosa. It also describes use of this combination in studies of allergic nasal mucosa and the effects of intranasal steroids before and during the allergy season. LÄS MER

5. 4. Pregnancy rhinitis : pathophysiological effects of oestrogen and treatment with oral decongestants

   Författare :Karin Toll; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Pregnancy rhinitis, a common condition, is thought to affect about 20 % of pregnant women. This type of rhinitis may develop at any time during pregnancy and the nasal stuffiness usually disappears shortly after delivery. This condition is troublesome and can interfere with sleep, induce tiredness and dryness of the mouth. LÄS MER

7. 5. Nasal and bronchial testing as well as treatment of patients with airway hyperresponsiveness and inflammation focusing on the united airway concept

   Författare :Anders Ehnhage; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Allergic and non-allergic rhinitis and asthma is a global health problem on the increase that causes major illness and disability worldwide, and also results in a large financial burden on society. This thesis contains six papers, based on four different clinical studies on humans with allergic as well as non-allergic airways inflammation, such as neutrophil inflammation caused by exposure to swine dust, as well as chronic rhinosinusitis and concomitant asthma with and without NSAID intolerance. LÄS MER