Sökning: "Alistair Chalk"

Hittade 1 avhandling innehållade orden Alistair Chalk.

1. 1. Computational prediction of antisense oligonucleotides and siRNAs

   Författare :Alistair Chalk; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Antisense oligonucleotides; siRNAs; Artificial neural networks; Support vector machines; prediction; specificity.;

   Sammanfattning : Two popular gene knockdown methods, antisense oligonucleotides (AOs) and short interfering RNAs (siRNAs) are commonly used to selectively inhibit gene expression (gene knockdown). This is an extremely valuable tool for functional genomics, however the selection of effective molecules using either method is non trivial. LÄS MER